Protein Alignment Pde9 and pde7a

DIOPT Version :10

• Sequence 1: NP_727644.3
• Gene: Pde9 / 32233
• FlyBaseID: FBgn0259171
• Length: 1623
• Species: Drosophila melanogaster
• Sequence 2: XP_005162725.2
• Gene: pde7a / 100151215
• ZFINID: ZDB-GENE-031222-10
• Length: 516
• Species: Danio rerio
• Alignment Length: 355
• Identity: 101/355 - (28%)
• Similarity: 161/355 - (45%)
• Gaps: 40/355 - (11%)

  Fly   621 DFRAL-----------VKDLKRKVEYTERMNWLCLSKRPL-GPPHRKSSLPKHQEVKRRFLEICD 673
            |||.|           .:.::|...:...:    ||.|.| |.||..   |.|         |.|
Zfish   117 DFRTLHSRAESAGSIPARRIRRLFSFQRHL----LSSRLLRGAPHLN---PLH---------ILD 165

  Fly   674 TTFSEEVRAALRLPA---FDSYEW----SDADVIHLMQTMFVELGFIEKFSIPVDTLREWLYEVY 731
            ..:..:.:..|....   ||.:.:    :...::.|...:..:.|.||.|.:.:..:|.:|..|.
Zfish   166 EDYCGQAKCMLEKVGSWNFDIFLFDRLTNGNSLVFLTFHLLSQYGLIELFQLDMVKVRRFLVLVQ 230

  Fly   732 KHY-NEVPFHNFRHCFCVAQMMYAITRQANLLSRLGDLECLILLVSCICHDLDHPGYNNIYQINA 795
            :.| |:.|:||..|...|.|.|:...|:..|...|...:.|:.|::...|||||||.|..:.|..
Zfish   231 EDYHNQNPYHNAVHAADVTQAMHCYLREPKLAQSLTSFDILLGLLAAATHDLDHPGVNQPFLIKT 295

  Fly   796 RTELALRYNDISPLENHHCSIAFRLLEHPECNIFKNFSRDTFNNIREGIIRCILATDMARHNEIL 860
            ...||..|.:.|.|||||...|..||.  |..:|.:...:...:|...:...|||||::|.||.|
Zfish   296 NHYLAALYRNTSVLENHHWRSAVGLLR--ETELFSHLPAEDSLSIERQLGSLILATDISRQNEYL 358

  Fly   861 TQFMEITPIFDYS--NRAHINLLCMILIKVADISNEARPMDVAEPWLDRLLQEFFAQSAAEKSEG 923
            ::|.......|.:  |.:|.:.:..:.:|.|||.|..||.::::.|.:::.:|||.|...||...
Zfish   359 SRFRTHLDENDLNLGNASHRHFVLQMALKCADICNPCRPWELSKQWSEKVTEEFFHQGDIEKKLK 423

  Fly   924 LPVTPFMDPDKVSKPGSQVRFIGLVLLPLF 953
            |.::|..|.:..:....|:.|:..|:.|||
Zfish   424 LEISPLCDSEANTIASVQIGFMTYVVEPLF 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pde9	NP_727644.3	PDEase_I	739..967	CDD:459723	71/217 (33%)
pde7a	XP_005162725.2	None