DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rnf128a and SPAC57A7.09

DIOPT Version :9

Sequence 1:	NP_997780.1	Gene:	rnf128a / 322325	ZFINID:	ZDB-GENE-030131-1044	Length:	389	Species:	Danio rerio
Sequence 2:	NP_593372.1	Gene:	SPAC57A7.09 / 2542187	PomBaseID:	SPAC57A7.09	Length:	372	Species:	Schizosaccharomyces pombe

Alignment Length:	355	Identity:	77/355 - (21%)
Similarity:	129/355 - (36%)	Gaps:	95/355 - (26%)

- Green bases have known domain annotations that are detailed below.

Zfish     4 LASRDVFSWLLLASVLQVSSVRLAEASYLCTAYLNISYTNPENNRSTWFQEEMGLYG----QDSP 64
            |..|:|..|    |...|.......||  .|..:|:..  |.|     |||:|.  |    .|:.
pombe    49 LPDRNVTLW----SRQAVFGKHFTNAS--ATTVINLYL--PSN-----FQEDMS--GCPNRNDTD 98

Zfish    65 KAYVKGN-------VYLASPTYGCDDDTFYGRPNGSKGW------IALIQRGNGCTFTEKINIAA 116
            .:|...|       .|:...:|.........:.:|.:..      ..|:|||. ||:.:|...|.
pombe    99 ASYFYENDIIDYDIEYIEQKSYSSKPSARVQKDDGGESKDEAILDFLLVQRGK-CTYFDKALEAQ 162

Zfish   117 MNGAAAAIIFN---------------DFGSENRVIQMSHPGTTIVAIMIGNYRGMELVQLLDQGV 166
            ..|....|:.:               |...|::|    |..:..|:....|....:|:....|.:
pombe   163 RLGFKGVIVGDNRSPSSFRLHYMVAPDKVDESKV----HIPSLFVSTSSYNLLWSDLLHSYRQPL 223

Zfish   167 PV-AIAIEVGKQHGPWMSHYSVFFVSISFFIVTAATVGYFIFYSARRLNSLRQQNRSQKKLKAEA 230
            .: |...|:|....|::..:|...:.:  ..|.|..:..||               ...:.|::.
pombe   224 KLYAKPEELGDMFWPFLLCFSPSIIML--ITVQALAIRKFI---------------RTYRTKSKT 271

Zfish   231 KKAIGQLQVRTL-RQG-------------DQEIGPDAD----------ACAVCIDSYKAGDVLSI 271
            ::.|..|..||: |:|             :.|:.|..|          .|.:|::|:..||.:..
pombe   272 RRFIEDLPSRTISREGFYSEEEEIENSTQNGELVPLMDESTRRATFGVECVICLESFTKGDKVVA 336

Zfish   272 LTCNHFFHKSCIEPWLLEHR-TCPMCKCDI 300
            |.|.|.||:.||..|::::| .||.|..::
pombe   337 LPCKHEFHRPCIAKWIVDYRHACPTCNTEV 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rnf128a	NP_997780.1	PA_GRAIL_like	38..172	CDD:239037	33/166 (20%)
rnf128a	NP_997780.1	zf-RING_2	256..297	CDD:290367	16/41 (39%)
SPAC57A7.09	NP_593372.1	COG5540	1..369	CDD:227827	77/355 (22%)
		Peptidases_S8_S53	<144..211	CDD:299169	16/71 (23%)
		zf-RING_2	320..362	CDD:290367	16/41 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4628
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810