DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Agpat1 and SLC1

DIOPT Version :9

Sequence 1:	NP_001259494.1	Gene:	Agpat1 / 32230	FlyBaseID:	FBgn0030421	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_010231.1	Gene:	SLC1 / 851508	SGDID:	S000002210	Length:	303	Species:	Saccharomyces cerevisiae

Alignment Length:	303	Identity:	106/303 - (34%)
Similarity:	158/303 - (52%)	Gaps:	54/303 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 FRYYFKFLM---------YYGIVSFNSIILIPAFLTRPCDV---RNLL-WASTWC--HRVSTLIG 78
            |.||.:.::         :||:::  ||:         |.:   ::|. |.:..|  |.:..::|
Yeast     7 FLYYLRSVLVVLALAGCGFYGVIA--SIL---------CTLIGKQHLAQWITARCFYHVMKLMLG 60

  Fly    79 LRWELRGKEHLAKDQACIIVANHQSSLDVLGMFNIWHVMNKCTVVAKRELFYAWPFGLAAW---L 140
            |..::.|:|:||| :..|::|||||:||:..:..|:  ...|||.||:.|.|. ||  ..|   |
Yeast    61 LDVKVVGEENLAK-KPYIMIANHQSTLDIFMLGRIF--PPGCTVTAKKSLKYV-PF--LGWFMAL 119

  Fly   141 AGLIFIDRVRGEKARETLNDVNRRIKKQRIKLWVFPEGTRRNTGALH--PFKKGAFHMAIDQQIP 203
            :|..|:||.:.::|.:|||.....:||.:..|||||||||..|..|.  ||||||||:|...:||
Yeast   120 SGTYFLDRSKRQEAIDTLNKGLENVKKNKRALWVFPEGTRSYTSELTMLPFKKGAFHLAQQGKIP 184

  Fly   204 ILPVVFSSYCTFLNDKKKILNSGRIVITTLPPVSTEGLTKDDIDVLMERVRSQMIETFK------ 262
            |:|||.|:..|.::.|..:.|.|.:::..|.|:|||.||||.|....|:||.||::|.|
Yeast   185 IVPVVVSNTSTLVSPKYGVFNRGCMIVRILKPISTENLTKDKIGEFAEKVRDQMVDTLKEIGYSP 249

  Fly   263 -----------VTSAEALHRYKPIKKVGIPAASSASTSSTTTT 294
                       :..|...|..|..||:......|.|.|:...|
Yeast   250 AINDTTLPPQAIEYAALQHDKKVNKKIKNEPVPSVSISNDVNT 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat1	NP_001259494.1	LPLAT_AGPAT-like	70..254	CDD:153251	81/190 (43%)
SLC1	NP_010231.1	AGP_acyltrn	60..191	CDD:129621	63/136 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341658
Domainoid	1	1.000	101	1.000	Domainoid score	I1544
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	147	1.000	Inparanoid score	I1139
Isobase	1	0.950	-	0	Normalized mean entropy	S1813
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001236
OrthoInspector	1	1.000	-	-		otm46929
orthoMCL	1	0.900	-	-		OOG6_100535
Panther	1	1.100	-	-	LDO	PTHR10434
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2233
SonicParanoid	1	1.000	-	-		X864
TreeFam	1	0.960	-	-
	14	13.730