DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Agpat1 and Lpcat2b

DIOPT Version :9

Sequence 1:	NP_001259494.1	Gene:	Agpat1 / 32230	FlyBaseID:	FBgn0030421	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_081875.1	Gene:	Lpcat2b / 70902	MGIID:	1918152	Length:	516	Species:	Mus musculus

Alignment Length:	252	Identity:	52/252 - (20%)
Similarity:	98/252 - (38%)	Gaps:	48/252 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VSFNSIILIPAFLTRPCDVRNLLWASTWCHRVSTLI-----------GLRWELRGKEHLAKDQAC 95
            |:..|.|.:|...|:|  :|.  |..   |.:.:.:           |...:::||:...::...
Mouse    79 VAVLSAINLPTQPTKP--IRR--WRK---HLIKSALVFLFRLGFFFAGFLVKVKGKKATREEAPI 136

  Fly    96 IIVANHQSSLDVLGMFNIWHVMNKCTVVAKRELFYAWPFGLAAWLAGLIFIDRVRGEKARETLND 160
            .:.|.|.:..|.:.:.    |....:||:..:|......|....:...:.:.|......:.|.|:
Mouse   137 FVSAPHSTFFDAIAVV----VAGLPSVVSDSQLARVPLAGKCILVTQPVLVKREDPNSRKTTRNE 197

  Fly   161 VNRRIKKQR--IKLWVFPEGTRRNTGALHPFKKGAFHMAIDQQIPILPVV--------------- 208
            :.||:|.:.  .::.:||||...|...|..||.|||    ...:|:.||:
Mouse   198 ILRRVKSKMKWPQILIFPEGLCTNRSCLVTFKLGAF----SPGVPVQPVLLRYPNSLDTVTWTWN 258

  Fly   209 -FSSYCTFLNDKKKILNSGRIVITTLPP-VSTEGLTKDDIDVLMERVRSQMIETFKV 263
             ||.:...:....::..  |:.:..:|. :.:|...||.| :....||.:|....|:
Mouse   259 GFSGFQVCMLTLSQLFT--RVEVEFMPVYIPSEEEKKDPI-LFANTVRIKMANALKL 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat1	NP_001259494.1	LPLAT_AGPAT-like	70..254	CDD:153251	40/213 (19%)
Lpcat2b	NP_081875.1	PlsC	65..307	CDD:223282	50/245 (20%)
		LPLAT_LPCAT1-like	111..323	CDD:153253	43/213 (20%)
		HXXXXD motif	142..147		1/4 (25%)
		EFh	392..454	CDD:238008
		EF-hand_7	392..453	CDD:290234
		EFh	429..487	CDD:298682
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810