DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat1 and Aup1

DIOPT Version :9

Sequence 1:	NP_001259494.1	Gene:	Agpat1 / 32230	FlyBaseID:	FBgn0030421	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_001073368.1	Gene:	Aup1 / 680423	RGDID:	1591777	Length:	410	Species:	Rattus norvegicus

Alignment Length:	311	Identity:	74/311 - (23%)
Similarity:	111/311 - (35%)	Gaps:	90/311 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LGLFLLLMLPFLYETNHIFRYYFKFLMYYGIVSFNSIILIPAFLTRPCDVRNLLWASTWCHRVST 75
            :||.||::..||  ..|:|           :||    ..:|..:.|...||      |.|    .
  Rat    34 VGLCLLVLRLFL--GLHVF-----------LVS----CALPDSVLRRFVVR------TMC----A 71

  Fly    76 LIGL--RWELRG-KEHLAKDQACIIVANHQSSLDVLGMFNIWHVMNKCTVVAKRELFYAWPFGLA 137
            ::||  |.|..| ::|..:    ::::||.:..|    .||.:::..|:......     |....
  Rat    72 VLGLVARQEDSGLRDHRVR----VLISNHVTPFD----HNIVNLLTTCSTPLLNS-----PPSFV 123

  Fly   138 AWLAGLIFIDRVRGEKARETLNDVNRRIKKQRIKLWVFP--EGTRRNTGALHPFKKGAFHMAIDQ 200
            .|..|.:.:|| |.|.. |:|.......:.....|.:||  |.|....|.|.
  Rat   124 CWSRGFMEMDR-RVELV-ESLKKFCASTRLPPTPLLLFPEEEATNGREGLLR------------- 173

  Fly   201 QIPILPVVFSSYCTFLNDKKKILNSGRIVITTL----PPVSTEGLTKDDIDVLMERVRSQMIETF 261
                    |||:...:.|..:.|        ||    |.||   :|..|...:.|.:.|..: .|
  Rat   174 --------FSSWPFSIQDVVQPL--------TLQVQRPLVS---VTVSDASWVSELLWSLFV-PF 218

  Fly   262 KVTSAEALHRYKPIKK-VGIPAASSA-STSSTTTTTLASPGTAVTPVADAA 310
            .|.....||   ||:: :|......| .........|...||.:|| ||.|
  Rat   219 TVYQVRWLH---PIRRQLGEENEEFALRVQQLVAKELGQIGTRLTP-ADKA 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat1	NP_001259494.1	LPLAT_AGPAT-like	70..254	CDD:153251	42/192 (22%)
Aup1	NP_001073368.1	LPLAT	66..264	CDD:302626	60/259 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	259..293		5/8 (63%)
		CUE_AUP1	300..340	CDD:270603
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	348..367
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900