DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat1 and lpcat1

DIOPT Version :9

Sequence 1:	NP_001259494.1	Gene:	Agpat1 / 32230	FlyBaseID:	FBgn0030421	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_001037806.2	Gene:	lpcat1 / 555969	ZFINID:	ZDB-GENE-060503-915	Length:	517	Species:	Danio rerio

Alignment Length:	134	Identity:	35/134 - (26%)
Similarity:	59/134 - (44%)	Gaps:	12/134 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 GLRW-ELRGKEHLAKDQACIIVANHQSSLDVLGMFNIWHVMNKCTVVAKRELFYAWPFGLAAWLA 141
            |..| .::|:..|..:...:.:|.|.|..|.:.:     .|...::|.|.|......:|......
Zfish   105 GFHWVRVKGRPALPSEAPILTMAPHSSYFDAIPV-----TMTMASIVMKAESKDIPVWGTLIKFI 164

  Fly   142 GLIFIDRVRGEKARETLNDVNRRIKK--QRIKLWVFPEGTRRNTGALHPFKKGAFHMAIDQQIPI 204
            ..:|:.|...:..|:|:.::.||...  :..::.:|||||..|...|..||.|||...    :|:
Zfish   165 RPVFVSRSDQDSRRKTVEEIKRRASSNGEWPQIMIFPEGTCTNRSCLIAFKPGAFIPG----VPV 225

  Fly   205 LPVV 208
            .|||
Zfish   226 QPVV 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat1	NP_001259494.1	LPLAT_AGPAT-like	70..254	CDD:153251	35/134 (26%)
lpcat1	NP_001037806.2	PlsC	52..>236	CDD:223282	35/134 (26%)
		LPLAT_LPCAT1-like	97..308	CDD:153253	35/134 (26%)
		HXXXXD motif. /evidence=ECO:0000250\|UniProtKB:Q3TFD2	129..134		2/4 (50%)
		EF-hand_7	413..472	CDD:290234
		EF-hand_8	424..475	CDD:290545
		Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q3TFD2	514..517
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810