DRSC/TRiP Functional Genomics Resources

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Protein Alignment Agpat1 and LPCAT2

DIOPT Version :9

Sequence 1:NP_001259494.1 Gene:Agpat1 / 32230 FlyBaseID:FBgn0030421 Length:343 Species:Drosophila melanogaster
Sequence 2:NP_060309.2 Gene:LPCAT2 / 54947 HGNCID:26032 Length:544 Species:Homo sapiens


Alignment Length:324 Identity:60/324 - (18%)
Similarity:100/324 - (30%) Gaps:131/324 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 LLGLFLLLMLPFLYETNHIFRYYFKFLMYYGIVSFNSIILIPAFLTRPCDVRNLLWASTWCHRVS 74
            |:.|.|||..||                     :..|.:..|..||.|        .:.|..:::
Human    72 LVALILLLAWPF---------------------AAISTVCCPEKLTHP--------ITGWRRKIT 107

  Fly    75 TLIGLRWELRGKEHLAKDQACIIVANHQSSLDVLG------MFNIWHVMNKCTVVAKRELFYAWP 133
                                       |::|..||      |..|..|..|.....:..:|.|.|
Human   108 ---------------------------QTALKFLGRAMFFSMGFIVAVKGKIASPLEAPVFVAAP 145

  Fly   134 F-----GLAAWLAGL------------------------IFIDRVRGEKARETLNDVNRRIKK-- 167
            .     |:|..:|||                        :.:.||..:..:.|:|::.:|...  
Human   146 HSTFFDGIACVVAGLPSMVSRNENAQVPLIGRLLRAVQPVLVSRVDPDSRKNTINEIIKRTTSGG 210

  Fly   168 QRIKLWVFPEGTRRNTGALHPFKKGAFHMAIDQQIPILPVVFS---------------------- 210
            :..::.||||||..|...|..||.|||...    :|:.||:..                      
Human   211 EWPQILVFPEGTCTNRSCLITFKPGAFIPG----VPVQPVLLRYPNKLDTVTWTWQGYTFIQLCM 271

  Fly   211 -SYCTFLNDKKKILNSGRIVITTLPPVSTEGLTKDDIDVLMERVRSQMIETFKVTSAEALHRYK 273
             ::|....         ::.:..:|........|:|..:...:||:.|.|...:...:  |.|:
Human   272 LTFCQLFT---------KVEVEFMPVQVPNDEEKNDPVLFANKVRNLMAEALGIPVTD--HTYE 324

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Agpat1NP_001259494.1 LPLAT_AGPAT-like 70..254 CDD:153251 41/243 (17%)
LPCAT2NP_060309.2 LPLAT_LPCAT1-like 116..327 CDD:153253 43/224 (19%)
HXXXXD motif. /evidence=ECO:0000250|UniProtKB:Q3TFD2 146..151 0/4 (0%)
EGTC motif 220..223 2/2 (100%)
EFh_PEF 374..494 CDD:330173
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 518..544
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0204
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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