DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat1 and Lpcat1

DIOPT Version :9

Sequence 1:	NP_001259494.1	Gene:	Agpat1 / 32230	FlyBaseID:	FBgn0030421	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_001094205.1	Gene:	Lpcat1 / 361467	RGDID:	1311599	Length:	534	Species:	Rattus norvegicus

Alignment Length:	231	Identity:	55/231 - (23%)
Similarity:	91/231 - (39%)	Gaps:	68/231 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ITMTSF-IELL--GLFLLLMLPFLY---------ETNHIFRYYFKFLMYYGIVSFNSIILIPAFL 54
            :|:|.| |.||  ...:||..||..         |.......:.|      :|.|    |:.|
  Rat    49 MTLTLFPIRLLFAAFMMLLAWPFALVASLGPPDKEPEQPLALWRK------VVDF----LLKA-- 101

  Fly    55 TRPCDVRNLLWASTWCHRVSTLIGLRWELRGKEHLAKDQACIIVANHQSSLDVLGMFNIWHVMNK 119
                 :...:|.:...|||:        ::|::.|..:.|.:.:|.|.|..|.:.:     .|..
  Rat   102 -----IMRTMWFAGGFHRVA--------VKGRQALPTEAAILTLAPHSSYFDAIPV-----TMTM 148

  Fly   120 CTVVAKRE----------LFYAWPFGLAAWLAGLIFIDRVRGEKARETLNDVNRRIKK--QRIKL 172
            .::|.|.|          :.|..|          :|:.|...:..|:|:.::.||.:.  :..::
  Rat   149 SSIVMKAESRDIPIWGTLIRYIRP----------VFVSRSDQDSRRKTVEEIKRRAQSNGKWPQI 203

  Fly   173 WVFPEGTRRNTGALHPFKKGAFHMAIDQQIPILPVV 208
            .:|||||..|...|..||.|||...    :|:.|||
  Rat   204 MIFPEGTCTNRTCLITFKPGAFIPG----VPVQPVV 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat1	NP_001259494.1	LPLAT_AGPAT-like	70..254	CDD:153251	38/151 (25%)
Lpcat1	NP_001094205.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25
		PlsC	59..>242	CDD:223282	50/221 (23%)
		LPLAT_LPCAT1-like	103..314	CDD:153253	39/160 (24%)
		HXXXXD motif. /evidence=ECO:0000250\|UniProtKB:Q3TFD2	135..140		2/4 (50%)
		EFh	<350..412	CDD:298682
		EFh	384..446	CDD:298682
		EF-hand_7	421..479	CDD:290234
		EF-hand_8	432..483	CDD:290545
		Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q3TFD2	531..534
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810