DRSC/TRiP Functional Genomics Resources

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Protein Alignment Agpat1 and Lpcat2

DIOPT Version :9

Sequence 1:NP_001259494.1 Gene:Agpat1 / 32230 FlyBaseID:FBgn0030421 Length:343 Species:Drosophila melanogaster
Sequence 2:NP_766602.1 Gene:Lpcat2 / 270084 MGIID:3606214 Length:544 Species:Mus musculus


Alignment Length:325 Identity:58/325 - (17%)
Similarity:100/325 - (30%) Gaps:133/325 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 LLGLFLLLMLPFLYETNHIFRYYFKFLMYYGIVSFNSIILIPAFLTRPCDVRNLLWASTWCHRVS 74
            |:|:.|||..||                     :..|....|..||.|        .|.|..:::
Mouse    72 LVGIILLLAWPF---------------------AVISTACCPEKLTHP--------ISNWRRKIT 107

  Fly    75 T------------LIGLRWELRGKEHLAKDQACIIVANHQSSLDVLGMFNIWHVMNKCTVVAKRE 127
            .            .:|....::||.....:....:||.|.:..|                     
Mouse   108 RPALTFLARAMFFSMGFTVTVKGKVASPLEAPIFVVAPHSTFFD--------------------- 151

  Fly   128 LFYAWPFGLAAWLAGL------------------------IFIDRVRGEKARETLNDVNRRIKK- 167
                   |:|..:|||                        :.:.||..:..:.|:|::.:|... 
Mouse   152 -------GIACVVAGLPSLVSRNENAQTPLVGRLLRALQPVLVSRVDPDSRKNTINEIKKRATSG 209

  Fly   168 -QRIKLWVFPEGTRRNTGALHPFKKGAFHMAIDQQIPILPVVFS--------------------- 210
             :..::.||||||..|...|..||.|||...    :|:.||:..                     
Mouse   210 GEWPQILVFPEGTCTNRSCLITFKPGAFIPG----VPVQPVLLRYPNKLDTVTWTWQGYTFLQLC 270

  Fly   211 --SYCTFLNDKKKILNSGRIVITTLPPVSTEGLTKDDIDVLMERVRSQMIETFKVTSAEALHRYK 273
              ::|....         ::.|..:|..:.....|:|..:...|:|:.|.|..::...:  |.|:
Mouse   271 VLTFCQLFT---------KVEIEFMPVQAPSEEEKNDPVLFASRIRNLMAEALEIPVTD--HTYE 324

  Fly   274  273
            Mouse   325  324

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Agpat1NP_001259494.1 LPLAT_AGPAT-like 70..254 CDD:153251 39/244 (16%)
Lpcat2NP_766602.1 PlsC 69..>254 CDD:223282 47/242 (19%)
LPLAT_LPCAT1-like 115..327 CDD:153253 44/253 (17%)
HXXXXD motif. /evidence=ECO:0000250|UniProtKB:Q3TFD2 146..151 1/4 (25%)
EGTC motif 220..223 2/2 (100%)
EFh 396..458 CDD:238008
EF-hand_7 396..457 CDD:290234
EF-hand_7 433..489 CDD:290234
EFh 433..486 CDD:298682
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 520..544
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0204
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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