DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat1 and Lpgat1

DIOPT Version :9

Sequence 1:	NP_001259494.1	Gene:	Agpat1 / 32230	FlyBaseID:	FBgn0030421	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_001128301.1	Gene:	Lpgat1 / 226856	MGIID:	2446186	Length:	409	Species:	Mus musculus

Alignment Length:	186	Identity:	43/186 - (23%)
Similarity:	86/186 - (46%)	Gaps:	44/186 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KFLMYYGIVSFNSIILIPAFL--------TRPCD------VRNLLW------ASTWCHRVSTLIG 78
            |.||.:..:..|:::.||:::        .|..|      :..|::      .::|.......:
Mouse    56 KALMRFAFMVANNLVAIPSYICYVIILQPLRVLDSKRFWYIEGLMYKWLLGMVASWGWYAGYTV- 119

  Fly    79 LRWELRGKE--HLAKDQACIIVANHQSSLDVLGMFNIWHVMNKCTVVAKR-----ELFYAWPFGL 136
            :.|   |::  .:|||:|.::| |||::.||..:  :..:.:|..|||:.     .:|....||:
Mouse   120 MEW---GEDIKAIAKDEAVMLV-NHQATGDVCTL--MMCLQDKGPVVAQMMWLMDHIFKYTNFGI 178

  Fly   137 AAWLAGLIFIDRVRGEKARETLNDVNRRIK---KQRIKLWV--FPEG----TRRNT 183
            .:.:.|..||.:.|..:.::.| .:.:.::   :.|.:.|:  ||||    .||.|
Mouse   179 VSLIHGDFFIRQGRAYRDQQLL-VLKKHLEHNYRSRDRKWIVLFPEGGFLRKRRET 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat1	NP_001259494.1	LPLAT_AGPAT-like	70..254	CDD:153251	33/130 (25%)
Lpgat1	NP_001128301.1	LPLAT_LCLAT1-like	108..324	CDD:153252	34/134 (25%)
Lpgat1	NP_001128301.1	Acyltransf_C	313..382	CDD:374349
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900