Protein Alignment Agpat1 and AGPAT2

DIOPT Version :10

• Sequence 1: NP_572828.1
• Gene: Agpat1 / 32230
• FlyBaseID: FBgn0030421
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_006403.2
• Gene: AGPAT2 / 10555
• HGNCID: 325
• Length: 278
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 93/276 - (33%)
• Similarity: 146/276 - (52%)
• Gaps: 21/276 - (7%)

  Fly    16 LLMLPFLYETNHIFRYYFKFLMYYGIVSFNSIILIPAFLTRPC-------DVRNLLWASTWCHRV 73
            ||:|..|.:.:....:|.|..:|..:     ...:.|..:..|       .|.|:.....:....
Human    11 LLLLLLLVQLSRAAEFYAKVALYCAL-----CFTVSAVASLVCLLRHGGRTVENMSIIGWFVRSF 70

  Fly    74 STLIGLRWELRGKEHLAKDQACIIVANHQSSLDVLGMFNIWHVMNKCTVVAKRELFYAWPFGLAA 138
            ....|||:|:|....|.:.:.|:||:||||.||::|:..:  :..:|..:|||||.:..|.||..
Human    71 KYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEV--LPERCVQIAKRELLFLGPVGLIM 133

  Fly   139 WLAGLIFIDRVRGEKARETLNDVNRRIKKQRIKLWVFPEGTRRNTGALHPFKKGAFHMAIDQQIP 203
            :|.|:.||:|.|...|...:.|:..|:.::.:|:|::|||||.:.|.|.|||||||::|:..|:|
Human   134 YLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGDLLPFKKGAFYLAVQAQVP 198

  Fly   204 ILPVVFSSYCTFLNDKKKILNSGRIVITTLPPVSTEGLTKDDIDVLMERVRSQMIETFKVTSAEA 268
            |:|||:||:.:|.|.|||...||.:.:..|..:.|.|||..|:..|::.....|..||
Human   199 IVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTF------- 256

  Fly   269 LHRYKPIKKVGIPAAS 284
            ||..|..::.|..|.|
Human   257 LHISKTPQENGATAGS 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Agpat1	NP_572828.1	PlsC	65..259	CDD:439974	74/193 (38%)
AGPAT2	NP_006403.2	PlsC	62..253	CDD:439974	73/192 (38%)
		HXXXXD motif. /evidence=ECO:0000250|UniProtKB:Q9D517	98..103		3/4 (75%)
		EGTR motif. /evidence=ECO:0000305|PubMed:21873652	172..175		2/2 (100%)