Protein Alignment Agpat1 and AGPAT2

DIOPT Version :9

• Sequence 1: NP_001259494.1
• Gene: Agpat1 / 32230
• FlyBaseID: FBgn0030421
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_006403.2
• Gene: AGPAT2 / 10555
• HGNCID: 325
• Length: 278
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 93/276 - (33%)
• Similarity: 146/276 - (52%)
• Gaps: 21/276 - (7%)

  Fly    16 LLMLPFLYETNHIFRYYFKFLMYYGIVSFNSIILIPAFLTRPC-------DVRNLLWASTWCHRV 73
            ||:|..|.:.:....:|.|..:|..:     ...:.|..:..|       .|.|:.....:....
Human    11 LLLLLLLVQLSRAAEFYAKVALYCAL-----CFTVSAVASLVCLLRHGGRTVENMSIIGWFVRSF 70

  Fly    74 STLIGLRWELRGKEHLAKDQACIIVANHQSSLDVLGMFNIWHVMNKCTVVAKRELFYAWPFGLAA 138
            ....|||:|:|....|.:.:.|:||:||||.||::|:..:  :..:|..:|||||.:..|.||..
Human    71 KYFYGLRFEVRDPRRLQEARPCVIVSNHQSILDMMGLMEV--LPERCVQIAKRELLFLGPVGLIM 133

  Fly   139 WLAGLIFIDRVRGEKARETLNDVNRRIKKQRIKLWVFPEGTRRNTGALHPFKKGAFHMAIDQQIP 203
            :|.|:.||:|.|...|...:.|:..|:.::.:|:|::|||||.:.|.|.|||||||::|:..|:|
Human   134 YLGGVFFINRQRSSTAMTVMADLGERMVRENLKVWIYPEGTRNDNGDLLPFKKGAFYLAVQAQVP 198

  Fly   204 ILPVVFSSYCTFLNDKKKILNSGRIVITTLPPVSTEGLTKDDIDVLMERVRSQMIETFKVTSAEA 268
            |:|||:||:.:|.|.|||...||.:.:..|..:.|.|||..|:..|::.....|..||
Human   199 IVPVVYSSFSSFYNTKKKFFTSGTVTVQVLEAIPTSGLTAADVPALVDTCHRAMRTTF------- 256

  Fly   269 LHRYKPIKKVGIPAAS 284
            ||..|..::.|..|.|
Human   257 LHISKTPQENGATAGS 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Agpat1	NP_001259494.1	LPLAT_AGPAT-like	70..254	CDD:153251	73/183 (40%)
AGPAT2	NP_006403.2	LPLAT_AGPAT-like	67..249	CDD:153251	73/183 (40%)
		HXXXXD motif. /evidence=ECO:0000250|UniProtKB:Q9D517	98..103		3/4 (75%)
		EGTR motif. /evidence=ECO:0000305|PubMed:21873652	172..175		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141868
Domainoid	1	1.000	135	1.000	Domainoid score	I4983
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	214	1.000	Inparanoid score	I3631
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1623097at2759
OrthoFinder	1	1.000	-	-		FOG0001236
OrthoInspector	1	1.000	-	-		otm42238
orthoMCL	1	0.900	-	-		OOG6_100535
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2233
SonicParanoid	1	1.000	-	-		X864
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.690