Protein Alignment Agpat1 and Lpcat2

DIOPT Version :10

• Sequence 1: NP_572828.1
• Gene: Agpat1 / 32230
• FlyBaseID: FBgn0030421
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_001258273.1
• Gene: Lpcat2 / 100359680
• RGDID: 2325051
• Length: 544
• Species: Rattus norvegicus
• Alignment Length: 325
• Identity: 59/325 - (18%)
• Similarity: 102/325 - (31%)
• Gaps: 133/325 - (40%)

  Fly    10 LLGLFLLLMLPFLYETNHIFRYYFKFLMYYGIVSFNSIILIPAFLTRPCDVRNLLWASTWCHRVS 74
            |:||.|||..||                     :..|.:..|..||.|        .|.|..:::
  Rat    72 LVGLVLLLAWPF---------------------AVISTVCCPKKLTHP--------ISDWRRKIT 107

  Fly    75 T------------LIGLRWELRGKEHLAKDQACIIVANHQSSLDVLGMFNIWHVMNKCTVVAKRE 127
            .            .:|.|..::||.....:....:||.|.:..|
  Rat   108 QPALKFLGRAMFFSMGFRVTVKGKVASPLEAPIFVVAPHSTFFD--------------------- 151

  Fly   128 LFYAWPFGLAAWLAGL------------------------IFIDRVRGEKARETLNDVNRRIKK- 167
                   |:|..:|||                        :.:.||..:..:.|:|::.:|...
  Rat   152 -------GIACVVAGLPSLVSRNENAQTPLVGRLLRALQPVLVSRVDPDSRKNTINEIKKRAMSG 209

  Fly   168 -QRIKLWVFPEGTRRNTGALHPFKKGAFHMAIDQQIPILPVVFS--------------------- 210
             :..::.||||||..|...|..||.|||...    :|:.||:..
  Rat   210 GEWPQILVFPEGTCTNRSCLITFKPGAFIPG----VPVQPVLLRYPNKLDTVTWTWQGYTFIQLC 270

  Fly   211 --SYCTFLNDKKKILNSGRIVITTLPPVSTEGLTKDDIDVLMERVRSQMIETFKVTSAEALHRYK 273
              ::|....         ::.:..:|..:.....::|..:...|||:.|.|..::...:  |.|:
  Rat   271 VLTFCQLFT---------KVEVEFMPVQAPSEEERNDPVLFASRVRNLMAEALEIPVTD--HTYE 324

  Fly   274  273
              Rat   325  324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Agpat1	NP_572828.1	PlsC	65..259	CDD:439974	43/254 (17%)
Lpcat2	NP_001258273.1	LPLAT_LPCAT1-like	116..327	CDD:153253	44/252 (17%)
		HXXXXD motif. /evidence=ECO:0000250|UniProtKB:Q3TFD2	146..151		1/4 (25%)
		EGTC motif	220..223		2/2 (100%)
		FRQ1	353..458	CDD:444056
		EFh	433..486	CDD:238008
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	520..544