DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HOXC6 and Antp

DIOPT Version :9

Sequence 1:	NP_004494.1	Gene:	HOXC6 / 3223	HGNCID:	5128	Length:	235	Species:	Homo sapiens
Sequence 2:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster

Alignment Length:	110	Identity:	70/110 - (63%)
Similarity:	78/110 - (70%)	Gaps:	13/110 - (11%)

- Green bases have known domain annotations that are detailed below.

Human   109 GRTAPQDQKASIQ-------IYPWMQRMNSHSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYL 166
            |:..|..|..:.|       :||||:     |..|...:|:||||.|:|||||||||||||||||
  Fly   263 GQHTPPSQNPNSQSSGMPSPLYPWMR-----SQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYL 322

Human   167 TRRRRIEIANALCLTERQIKIWFQNRRMKWKKESNLTSTLSGGGG 211
            |||||||||:||||||||||||||||||||||| |.|....|.||
  Fly   323 TRRRRIEIAHALCLTERQIKIWFQNRRMKWKKE-NKTKGEPGSGG 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HOXC6	NP_004494.1	Antp-type hexapeptide	122..127		3/4 (75%)
		Homeobox	145..198	CDD:395001	49/52 (94%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	200..235		5/12 (42%)
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	16/47 (34%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	49/52 (94%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45659
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2625
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.940