Protein Alignment pira and si:dkey-100n23.3

DIOPT Version :10

• Sequence 1: NP_572827.1
• Gene: pira / 32229
• FlyBaseID: FBgn0030420
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: XP_005167827.1
• Gene: si:dkey-100n23.3 / 571373
• ZFINID: ZDB-GENE-070912-345
• Length: 991
• Species: Danio rerio
• Alignment Length: 768
• Identity: 188/768 - (24%)
• Similarity: 290/768 - (37%)
• Gaps: 230/768 - (29%)

  Fly     2 DRKETVS--KDQAVRRIAHNDFILVSRQLLINRADTDPDKGSARMLIIYSSGKQHIVTFKLPNLA 64
            :|:|:..  ||.|    .|.:..|.|...|:.  :.:..:||...|   |:|    ..|::|...
Zfish   283 ERRESQESPKDAA----KHEENHLCSNGELVQ--EVEGMRGSVLRL---SAG----TDFQIPVKR 334

  Fly    65 CRV----QDLFFQMDLQID----ESTTIDCIENAGGIIHLVVSVGFPISDNIAETVAHAEEFYRK 121
            ||:    :|.....||..|    .|.|::             |..|...:.|..:....:|...:
Zfish   335 CRLDSLSEDQLLNSDLAFDTAEIRSFTLE-------------SSNFSQDETIVLSSEEEDEGEGR 386

  Fly   122 VHQSKASSADAAPPNAMAGEEHSPAVVKPSETAVANNGCQPAASATKGKKHKKSPCGSP------ 180
             .::|.|:.:..||     |......|....|.|......|.::.:..:..::...|.|
Zfish   387 -EETKISALNIQPP-----EGTKDTNVVDESTTVYEQTKSPESNLSITEMSEEESQGIPLPLSSL 445

  Fly   181 -----GENNDGQVIL------------SADQDANTNTKAKKQKK-----------CHIAKDN--- 214
                 ...:.|.:::            |:|.....:..|....|           |.:.|||
Zfish   446 HMGGVSAKSSGIMMITPYKITFSLKGNSSDSTVKISLSAINVYKYSLWEEHTLWGCDLDKDNEAT 510

  Fly   215 ---------NGIQAASSHDN---------PSSSG---------------------------NKQG 234
                     :..||...||:         |:.|.                           :.||
Zfish   511 PTSLLFLWLSDAQAHKLHDDLSVLELGTRPAESSTCLLLCMAEPLSGIESALLCSLLDIVVSNQG 575

  Fly   235 SHN--STAITSNSTMTSNGLRGVQPAEDAPAISQWIQSRNNAAVSKKSEETAGGSQSRVQSNVAS 297
            |..  .|.:|.     |:.|..:|.:|:...:        .....|..|:|:..:||:
Zfish   576 SPELYCTCLTQ-----SDSLNLLQSSEETHLL--------QLLTPKPDEQTSTSAQSQ------- 620

  Fly   298 ISSPAVKATSDAAIPTPAERAERSRLRRNRNWILSRDVDEDAVVLVSSGDEETTAADDGQTERRL 362
                    .||..: .|.......|.:.:.|..|:          .:.|.|.|.....|.|.|.:
Zfish   621 --------DSDVQL-EPTYTLCHRRAQGSYNVFLA----------ATPGAEWTPYKHCGPTRRLI 666

  Fly   363 S-PDENQTLFTYPPTGTGGLSITIKDFMCLSKGSYLNDIIIDFYLRWLKNNIIPEEQRDRTHIFS 426
            . |         ||...|.|::|.:|..||..|.:|||:||||||::|.....|:....|:||||
Zfish   667 QFP---------PPPSKGALTVTTEDLECLDSGEFLNDVIIDFYLKYLLVQKAPQASVARSHIFS 722

  Fly   427 TFFHKRLTTRTNPR--NTKQTAAQKRHERVEKWTRNVNIFDKDFIIIPFNEQSHWILAIICYPNL 489
            :||:|:||.|.|..  :|...|..:||:||..|||:|:||:|||:.:|.|:::||.|.:||:|.|
Zfish   723 SFFYKQLTRRDNANEDSTSTPAQVRRHQRVRTWTRHVDIFEKDFLFVPVNQEAHWYLVVICFPGL 787

  Fly   490 RSP------------------VVNNNN--------------------------------VQTTLS 504
            ..|                  |..:.|                                .:.|..
Zfish   788 EDPQYVKRDDSASVQGNGGEDVGESENETQGDHRSNSDEDKSTDDSRIKSSTSLRQPDCTENTCK 852

  Fly   505 DDIPIKQPLILIFDSLAVTSRHRAIAILRDYLTCEHKAKYPNALAHVFNKDNMPGHSVEVPQQQN 569
            .|:.:|:|.|||.|||.::...|...:||:||..|.:.|...  ...|:.:.|.|...:||.|.|
Zfish   853 KDVVLKRPCILIMDSLKLSIHERIFKLLREYLQVEWETKRMG--TRDFSAERMVGSHCKVPLQDN 915

  Fly   570 LTDCGLYLLQYVEQFFTKPINDYTLPIKELSNWFDLLTVTKKREDIANLIKKL 622
            .:|||||||||.|.|...|:..:.||:: |..||....|..||::|.:||..|
Zfish   916 SSDCGLYLLQYAESFLQDPVVHFDLPLR-LERWFPRQQVRGKRDEIRDLILHL 967

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pira	NP_572827.1	Peptidase_C48	396..585	CDD:420019	84/240 (35%)
si:dkey-100n23.3	XP_005167827.1	Peptidase_C48	691..939	CDD:420019	86/249 (35%)