Protein Alignment pira and Semp2l2a

DIOPT Version :10

• Sequence 1: NP_572827.1
• Gene: pira / 32229
• FlyBaseID: FBgn0030420
• Length: 681
• Species: Drosophila melanogaster
• Sequence 2: NP_694733.3
• Gene: Semp2l2a / 231201
• MGIID: 2667157
• Length: 502
• Species: Mus musculus
• Alignment Length: 510
• Identity: 110/510 - (21%)
• Similarity: 178/510 - (34%)
• Gaps: 164/510 - (32%)

  Fly   124 QSKASSADAAPPNAMAGEEHSPAVVK--PSETAVANNGCQPAASATKGKKHKKSPCG-------S 179
            :.:.|......|.....::..|..:.  |.|.||  .|.:||..   ||.||: |..       |
Mouse    74 REQPSKGQVRKPQGKTPKQLKPLELTEGPPEQAV--TGRKPADG---GKGHKR-PYSVMEENEQS 132

  Fly   180 PGENNDGQVI--LSADQDAN----------TNT-KAKKQKKCHIAKDNNGIQAASSHDNPSS--- 228
            |.:...|:::  |..|||..          ||| |.|..:    :.|::|.:...|:..||:
Mouse   133 PQKEKYGRLLQHLQCDQDVRSDQHRPHPILTNTWKIKGGE----SGDSHGSERIQSNREPSTVAA 193

  Fly   229 -------SGNKQGSHNSTAIT-SNSTMTSNGLRGVQPAEDAPAISQWIQ-----SRNNA------ 274
                   .|.::.......:| ....:...|.||.....|.|  ..|.|     .|.|:
Mouse   194 LKECLSPEGREKCCSEEKCVTEKKGCVKGEGRRGNSLEPDLP--ETWAQIILDSGRGNSLLPNKV 256

  Fly   275 ---AVSKKSEETAGGSQSRVQSNVASISSPAVKATSDAAIPTPAERAERSRLRRNRNWILSRDVD 336
               |..||.....|  :.|....:..||....|...:|..|.|.|....||.:
Mouse   257 AVLAAEKKPITDQG--KGRKMDQILDISEDMEKEIENALGPGPQEEILSSRFK------------ 307

  Fly   337 EDAVVLVSSGDEETTAADDGQTERRLSPDENQTLFTYPPTGTGGLSITIKDFMCLSKGSYLNDII 401
                :.:|.||.:|                                        |..|.:|||.:
Mouse   308 ----LQISRGDIQT----------------------------------------LENGQWLNDEV 328

  Fly   402 IDFYLRWLKNNIIPEEQRDR----THIFSTFFHKRLTTRTNPRNTKQTAAQKRHERVEKWTRNVN 462
            |:||:     |::.|...::    .|:|||||:.:|             ....:..|::|||.:|
Mouse   329 INFYM-----NLLVERNENQGYPALHVFSTFFYPKL-------------KHSGYSSVKRWTRGIN 375

  Fly   463 IFDKDFIIIPFNEQSHWILAIICYPNLRSPVVNNNNVQTTLSDDIPIKQPLILIFDSLAVTSRHR 527
            :|:|:.|::|.:::.||.|.:                       |.:::..|:..||:..|.:..
Mouse   376 LFEKELILVPIHQRVHWSLVV-----------------------IDLRKRSIVYLDSMGQTGKSI 417

  Fly   528 AIAILRDYLTCEHKAKYPNALAHVFNKDNMPGHSVEVPQQQNLTDCGLYLLQYVE 582
            ...|.: ||..|.|.: .|..............|.|:|.|.|.:|||::..:|.:
Mouse   418 CETIFQ-YLQNESKTR-RNIELDPLEWKQCSVTSEEIPLQLNGSDCGVFTCKYAD 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pira	NP_572827.1	Peptidase_C48	396..585	CDD:420019	47/191 (25%)
Semp2l2a	NP_694733.3	Peptidase_C48	<279..497	CDD:420019	62/291 (21%)