DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12717 and ulp-4

DIOPT Version :9

Sequence 1:	NP_001285167.1	Gene:	CG12717 / 32229	FlyBaseID:	FBgn0030420	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	NP_495703.2	Gene:	ulp-4 / 174307	WormBaseID:	WBGene00006739	Length:	382	Species:	Caenorhabditis elegans

Alignment Length:	337	Identity:	72/337 - (21%)
Similarity:	142/337 - (42%)	Gaps:	78/337 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   335 VDEDAVVLVSSGDEETTAADDGQTERRLSPDENQTLF---------TYPPTGTGGLSITIKDFMC 390
            ||||.       :||....:|..|.::.:.::|...:         .:|   ...::|.|.||.|
Worm    86 VDEDE-------EEEDEEDNDEWTNQKRTDNQNSVAYYAAMEMLRIRFP---FQSIAIRISDFCC 140

  Fly   391 LSKGSYLNDIIIDFYLRWLKNNIIPEEQRDRTHIFSTFFHKRLTTRTNPRNTKQTAAQKRHERVE 455
            |.:...|||.:|||||..:..:::|:.......:..:.|...|:.|.:..:::........::::
Worm   141 LQEKDLLNDTMIDFYLNHIVEHVLPDSNGSNVTVLPSIFWHNLSLRQHAFDSEDEKMMSDEQKMD 205

  Fly   456 -------KWTRNVNIFDKDFIIIPFNEQSHWILAIICYPNLRSPVVNNNNVQTTLSDDIPIKQPL 513
                   .:..:.::.|.|:|::|.||..||.||:||:|.                    ..|..
Worm   206 LKFGDLHDFVADFDLQDFDYIVVPVNEWEHWSLAVICHPF--------------------TAQAR 250

  Fly   514 ILIFDS---LAVTSRHRAIAILRDYLTCEHKAKYPNALAHVFNKDNMPGHSV---EVPQQQNLTD 572
            .:||||   ..:.:......::..::...::.:..||:.       .|...:   .:|||.|..|
Worm   251 TVIFDSQLTADLNNLQNMATLIESFMKYSYEKRTGNAMP-------FPLPCILPQRMPQQTNNFD 308

  Fly   573 CGLYLLQYVEQFFTKPINDYTLPIKELSN------WFDLLTVTKKREDIANLIKKLMNESNQQRK 631
            ||:::.::..:|...|      | |:|.|      :.|..|.||:.|    :.:.:::.|..:.:
Worm   309 CGIFIAEFARRFLLSP------P-KDLDNFDFAREYPDFSTATKRTE----MQRVVLSLSTNRAR 362

  Fly   632 ILPVIKFPTLNG 643
            ..|:::.  |||
Worm   363 WRPLVEL--LNG 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12717	NP_001285167.1	BASP1	122..319	CDD:283191
CG12717	NP_001285167.1	Peptidase_C48	396..585	CDD:304959	40/201 (20%)
ulp-4	NP_495703.2	Peptidase_C48	145..333	CDD:304959	46/221 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166373
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6692
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000929
OrthoInspector	1	1.000	-	-		otm14648
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1602
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.720