DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12717 and senp7

DIOPT Version :9

Sequence 1:	NP_001285167.1	Gene:	CG12717 / 32229	FlyBaseID:	FBgn0030420	Length:	681	Species:	Drosophila melanogaster
Sequence 2:	XP_031752848.1	Gene:	senp7 / 100495461	XenbaseID:	XB-GENE-1000860	Length:	900	Species:	Xenopus tropicalis

Alignment Length:	810	Identity:	198/810 - (24%)
Similarity:	305/810 - (37%)	Gaps:	216/810 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KETVSKDQAVRRIAH---------NDFILVSRQLLINRADTDPD---KGSARMLIIYSSGKQ--- 53
            :||:.:.:|.|.:::         |.......|:....:..:|:   |....|:...|..|:
Frog   124 QETIQQSKACRDVSNTSNSSLKETNSRRSYYEQVTSGSSQKEPEQETKSPVNMISSPSKSKRDRT 188

  Fly    54 ---------HIVTFKLP---NLACRVQDLFFQMDLQIDESTTIDCIENAGGIIHLVVSVGFPISD 106
                     |..:..||   ::......|...:.|..|.       .|.|.:..|..:.|..::.
Frog   189 YCQKLAEQMHNKSSLLPEQDSVCVNASPLEENLHLSTDS-------PNIGSVSTLKSNSGTTLTG 246

  Fly   107 NIA-------ETVAHAEEFYR--KVHQSKASSADAAPPNAMAGEEHSPAVVKPSETAVANNGCQP 162
            :|:       .|..:.:.|.|  |.|.|..::..::.|..::.:|...:..:.:| :|.......
Frog   247 DISGSPNLVKHTSNNVQLFKRNVKTHISNKATPSSSEPIVLSSDEEERSHGETAE-SVMEKPLTE 310

  Fly   163 AASATKGKKHKKSPCGS----------PGENNDGQVILSADQDA--------NTNTKAKKQKKCH 209
            .....:|.:|.:..|..          ||:    :::.|...::        |.....:|.:...
Frog   311 MIDMNEGTEHNQLSCNETSKLMKHVYLPGK----EILFSVLPESKVLELEFMNAYIGTRKGRTIG 371

  Fly   210 IAKDNNGIQAASSHDNPSSSGNKQGSHNSTAITSNSTMTSNGLRGVQP--AEDAPAISQWIQSRN 272
            .||     ..|.|.|.|.....::   |.|...|.:.:...|:.....  ......|..|:.|.|
Frog   372 PAK-----FTAKSIDIPLRVTLQK---NCTVSFSTAVLCKYGVWETDKDFVRSRAIIFLWVSSDN 428

  Fly   273 -------------------------NAAVSKKSEETAGGSQSRVQSNVASISSPAVKATSD---- 308
                                     |..:|||.::..    :.:.:..:...||.:|....
Frog   429 DIEMQLGTSIKNPVSKPVEFIFLELNVMLSKKEQDVL----NEIMNEASKKGSPGLKDIMSWQMA 489

  Fly   309 ------------------------------AAIPTPAERAERSRLRR--NRNWILSRDVDEDAVV 341
                                          .|:..|...:|.|..::  |...:|.|....
Frog   490 CPLFKDLPLAENAFMSNCLPAFQKQQPHPPEALTLPEHSSECSSPKQAPNTYTLLQRQTGR---- 550

  Fly   342 LVSSGDEETTAADDGQTERRLSPDENQTLFTYPPTGT-GGLSITIKDFMCLSKGSYLNDIIIDFY 405
            |.|:  ......|:|.||.| .......|..|||..| |||.:|.:|..||..|.:|||:|||||
Frog   551 LYSA--SLVPKQDNGWTEMR-HAGSLLKLIVYPPPPTKGGLCVTNEDLDCLEHGEFLNDVIIDFY 612

  Fly   406 LRWLKNNIIPEEQRDRTHIFSTFFHKRLTTR---TNPRNTKQTAAQKRHERVEKWTRNVNIFDKD 467
            |::|.....|:...:|:||||:||:|.||.:   .|.......|||:||:||:.|||:|:||.||
Frog   613 LKYLLLERFPKHFAERSHIFSSFFYKCLTRKEIAANESCASLPAAQRRHQRVKTWTRHVDIFTKD 677

  Fly   468 FIIIPFNEQSHWILAIICYPNLRSPVVNNNNVQTT------------------------------ 502
            ||.:|.||.|||.||:||:|.|.|......|..:|
Frog   678 FIFVPVNENSHWYLAVICFPWLESAEFEERNFDSTNLCGKPPKEASNTTCSVIVFNDHLEKEEET 742

  Fly   503 -----LSDDIP------------------------IKQPLILIFDSLAVTSRHRAIAILRDYLTC 538
                 .|||..                        .|:|.:||||||...|....:.:||:||..
Frog   743 IVDDSSSDDSTRPSPHSGSNKKKSRETKGNLCRKVCKRPCLLIFDSLKSGSVQTTVQVLREYLKV 807

  Fly   539 EHKAKYPNALAHVFNKDNMPGHSVEVPQQQNLTDCGLYLLQYVEQFFTKPINDYTLPIKELSNWF 603
            |.:.|  ......|::.||.....:||:|.|.|||||:||||||.|..:||.::..|| .|.:||
Frog   808 EWEVK--RKTMREFSRSNMRDFYPKVPKQNNSTDCGLFLLQYVESFVQQPIENFDSPI-HLEDWF 869

  Fly   604 DLLTVTKKREDIANLIKK--LMNESNQQRK 631
            .|..|..|||:|.:||.|  |..:.|...|
Frog   870 PLTVVKSKREEIRDLILKLHLQQDGNSGNK 899

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12717	NP_001285167.1	BASP1	122..319	CDD:283191	37/275 (13%)
CG12717	NP_001285167.1	Peptidase_C48	396..585	CDD:304959	90/250 (36%)
senp7	XP_031752848.1	ULP1	<572..861	CDD:227489	106/290 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I3701
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000929
OrthoInspector	1	1.000	-	-		otm49328
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X756
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.000