DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Paics and PUR7

DIOPT Version :9

Sequence 1:	NP_572826.1	Gene:	Paics / 32228	FlyBaseID:	FBgn0020513	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001030739.1	Gene:	PUR7 / 821663	AraportID:	AT3G21110	Length:	411	Species:	Arabidopsis thaliana

Alignment Length:	319	Identity:	87/319 - (27%)
Similarity:	127/319 - (39%)	Gaps:	77/319 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TTTTASIEGYKLGKVIIEGKTKQVYDLPEQPGLCLLLSKDRITAGDGVKAHDLAGKAEISNTTNG 67
            |...|::.|.|..   |:||.:.:||..:   ..:|::.||::|.|    .:||     |....|
plant    97 TNLLATVPGLKSR---IKGKVRDIYDAGD---YLVLITTDRLSAFD----RNLA-----SIPFKG 146

  Fly    68 QVFRLLNEAGI----------RTAYVKQCGAKAFIARKCQMIPIEWVTRRLATGS-----FLKRN 117
            ||   |||..:          ..|.|........||:||.:.|||:|.|...|||     :...|
plant   147 QV---LNETSLWWFNNTQHITPNAIVSSPDRNVVIAKKCSVFPIEFVVRGYVTGSTDTSLWTVYN 208

  Fly   118 VGVPE--GYRFS---------PPKQETFFKDDANHDPQWSEEQIVSAKFELNGLVIGQDEVDIMR 171
            .||..  |...|         |....|.....|:||...|..:||...|      :.|.|.|...
plant   209 KGVRNYCGNELSDGLVKNQKLPANILTPTTKAADHDVPISPNEIVEGGF------MTQAEFDEAS 267

  Fly   172 RTTLLVFEILERAWQTKNCALIDMKVEFGICDDGNIVLADIIDS-DSWRLWPAG--DKRLM---- 229
            ...|.:||..:...:.....|:|.|.|||...||:|:|.|.|.: ||.|.|.||  ::|..
plant   268 MKALSLFEFGQGVAKKHGLILVDTKYEFGRSSDGSILLIDEIHTPDSSRYWLAGSYEERFQKGLE 332

  Fly   230 ---VDKQVYR-------------NLASVTASDLDTVKRNFIWVAEQLA----DIVPKKD 268
               |||:..|             .|.:..|..:..:...:|::.|.:.    ||:|.::
plant   333 PENVDKEFLRLWFKENCNPYEDEVLPAAPAELVTELAWRYIFLYETITGSRIDIIPTQE 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Paics	NP_572826.1	SAICAR_synt_Ade5	12..260	CDD:133471	81/296 (27%)
Paics	NP_572826.1	purE	271..424	CDD:273474
PUR7	NP_001030739.1	PLN02544	32..401	CDD:178159	87/319 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	59	1.000	Domainoid score	I3919
eggNOG	1	0.900	-	-		E1_COG0152
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2538
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D566769at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto3499
orthoMCL	1	0.900	-	-		OOG6_101413
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.770