Protein Alignment rad21a and vtd

DIOPT Version :10

• Sequence 1: NP_955889.1
• Gene: rad21a / 322275
• ZFINID: ZDB-GENE-030131-994
• Length: 643
• Species: Danio rerio
• Sequence 2: NP_001015132.1
• Gene: vtd / 3354896
• FlyBaseID: FBgn0260987
• Length: 715
• Species: Drosophila melanogaster
• Alignment Length: 748
• Identity: 283/748 - (37%)
• Similarity: 401/748 - (53%)
• Gaps: 146/748 - (19%)

Zfish     1 MFYAHFVLSKRGPLAKIWLAAHWDKKLTKAHVFECNLESSVESIISPKVKMALRTSGHLLLGVVR 65
            |||.|.:|:|:||||:||||||||||:|||||||.|:|.|||.|:.||||:||||||||||||||
  Fly     1 MFYEHIILAKKGPLARIWLAAHWDKKITKAHVFETNIEKSVEGILQPKVKLALRTSGHLLLGVVR 65

Zfish    66 IYHRKAKYLLADCNEAFIKIKMAFRPGVVDLPEDNREAAYNAITLPEEFHDFDQPLPDLDDIDVA 130
            ||.||||||||||||||:|||||||||:|||||.:|||..|||||||.|||||..||:|:|||:.
  Fly    66 IYSRKAKYLLADCNEAFVKIKMAFRPGMVDLPEGHREANVNAITLPEVFHDFDTALPELNDIDIE 130

Zfish   131 QQFTLNQSRVEEITMREEVGNISL-MTDNDFGDFGMDDR--EMMR-------EENAFGDIIHESS 185
            .||::||||.:||||||:.|::|| :.|:.|||.|.:..  |::|       .:..|.:.:.|:.
  Fly   131 AQFSINQSRADEITMREDYGSLSLSLQDDGFGDIGFEAETPEIIRCSIPSNINDKIFDNDVLENI 195

Zfish   186 AANLLLEAEPGPAHLPDKTPNLDYDDFGDNNLENSDGGILMDKILSNEDGGGIFDDPPAITDSV- 249
            .:   |:.....||.......||.|.|||:         .....|..:|   :|.||....:.:
  Fly   196 ES---LDPHSLDAHADMPGSRLDGDGFGDS---------FGQPALFEDD---LFGDPSQPVEQIT 245

Zfish   250 -----MMPQDHGDDD--DDFDNF-SPAGG-----PDSPDSGPVEPLPNTTDQTDQTEQTTLVPNE 301
                 ::..|..|:|  |:..|. |||..     .|..:...:....:.::.....| .|||.||
  Fly   246 KESTTVLNADDSDEDAIDNIHNVPSPATSLVNSIEDEKEENNLNGHASVSENVPMNE-ITLVQNE 309

Zfish   302 DEAFALEPIDITVKE--TKAKRKRKLIVDSLKELDSKTIRAQLSDYSDIVTTLDLAPPTKKLMMW 364
            ||.|||.|:|:::.:  ||||||||||:|.:|.:..:.::|||:|.|||:||||||||||:||.|
  Fly   310 DEGFALAPLDVSMYKGVTKAKRKRKLIIDEIKNISGEEMKAQLADTSDILTTLDLAPPTKRLMYW 374

Zfish   365 KETGGVEKLFSLPAQPL--------WNGRLL--KMFTRCLTPLVPDEL----------------- 402
            |||||||||||||::.:        :|.:|.  ..|....:.:||.|:
  Fly   375 KETGGVEKLFSLPSRSIPARALFGNYNRQLFSHSTFFEDFSSVVPMEILALEFYTKENENALIIF 439

Zfish   403 ---RKRRKGGEADSL------EDFLKELENPEVPR-------------------EEVLGHRSDVI 439
               .::||.....:|      :..::.||.|||.|                   :|.:..::::.
  Fly   440 NKKGRKRKNDNMSNLFLDHVPDSVVQSLEAPEVLRANHKSLGVSTVSVEIVSKEQESISCQNELT 504

Zfish   440 DQTIMEEPSMLQASSMEGSRTALDESMMPP--------------PSRQRGL-------KRKSLET 483
            ....|..|.:|..:.|| ..::::|..:.|              .|...||       :..::..
  Fly   505 FFDNMRSPDLLSLNEME-QFSSINELPLTPRNMNHEMGDDFNQGDSTPAGLDHGHATPQHGNIGE 568

Zfish   484 LEKDAVLPPMGVLEQTLQPLDQSVLSHQLEMPQVELPPEDTTNLSR-----LIPELDLLDEKSKD 543
            ::.|:|:|    .::|...|::||.:..|....|.   :.|.|:.:     .||..
  Fly   569 MDHDSVIP----TKKTAVILNESVGTSVLSDNGVS---KRTNNILKGWDNYEIPSF--------- 617

Zfish   544 KDKDDSDEEGEEGQGGDQDQEERRWNKRTQQMLHGLQ-RVVAKTGAQSIGLLELCRNNNKKQAAA 607
            ..::..||:.|...  |:..|||..|||...:...:: ..:||   .|:.|.:|...|::||||.
  Fly   618 VGQNHGDEQMENET--DEQFEERVLNKRAAHLFIDVRAHFIAK---DSLELSQLTSGNSRKQAAQ 677

Zfish   608 KFYSFLVLKKQQAIDLTQTEPYSDIIAAPGPRF 640
            ||||.|||||.:.:.:.|:.||:||....||.|
  Fly   678 KFYSLLVLKKFKVLHIDQSAPYADITITRGPTF 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rad21a	NP_955889.1	Rad21_Rec8_N	1..104	CDD:461446	83/102 (81%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	234..298		15/77 (19%)
		Rad21_Rec8_M_NXP1-like	317..396	CDD:439294	48/88 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	447..479		9/52 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	532..566		6/33 (18%)
		Rad21_Rec8	586..640	CDD:335912	24/53 (45%)
vtd	NP_001015132.1	Rad21_Rec8_N	1..103	CDD:461446	82/101 (81%)
		Rad21_Rec8_M_NXP1-like	327..404	CDD:439294	46/76 (61%)
		Rad21_Rec8	657..710	CDD:335912	26/55 (47%)