DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15725 and Nacc2

DIOPT Version :10

Sequence 1:NP_572823.1 Gene:CG15725 / 32224 FlyBaseID:FBgn0030417 Length:745 Species:Drosophila melanogaster
Sequence 2:NP_080771.3 Gene:Nacc2 / 67991 MGIID:1915241 Length:586 Species:Mus musculus


Alignment Length:610 Identity:118/610 - (19%)
Similarity:196/610 - (32%) Gaps:180/610 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    63 FVAHSLVLGMHSGYLRSAIRLDETAAGTAASVSASASISITGATAASCNPSSSSSAASSSSSAVT 127
            |.||..||...|.|.|...           |.::.::..:.|....:|                 
Mouse    41 FKAHRAVLAASSLYFRDLF-----------SGNSKSAFELPGTVPPAC----------------- 77

  Fly   128 TASGELLLYLSNVTADQFAPLLTYMYTGYLDLNVDNIFAVLLATHVLHMPRALE----------- 181
                             |..:|::.|||.|.:.......|:.....|.:...:|           
Mouse    78 -----------------FQQILSFCYTGKLTMAASEQLVVMYTAGFLQIQHIVERGTDLMFKVSS 125

  Fly   182 -ICRSFLARAQTEGYLNGNPAAQLCPV-------PSIPAKII---------------------RP 217
             .|.|..|..:.......:|..||.|.       ||:|..::                     ||
Mouse   126 PHCDSQTAMIEDASSEPQSPCNQLQPATAAYVTSPSVPIPLLTRVKHEAMEMPPASGPGLASKRP 190

  Fly   218 IPS-----------KATMPNFGFLPLPQAP----PSVA---PSAQPTAHQPTTGIAPVASASILS 264
            :.:           .|..|....|.||:..    ||:|   ||.|...:.|....:|.|| |:.:
Mouse   191 LETGPRDGVAVATGAAGTPGTAPLKLPRVSYYGVPSLATLIPSIQQVPYPPGERTSPGAS-SLPT 254

  Fly   265 SFGTNTQHMEHMEQPIAMLDNEVDEEDVEVFIDSNTVTDNEAEELEPD-VDMDCN---------V 319
            :....:.|.|..|:.....|..|:|:..:::|.:   |.|.|.:.:|: |.::..         |
Mouse   255 TDSPTSYHNEEDEEDDEAYDTMVEEQYGQMYIKA---TGNYAVQEKPEPVPLESRSCVLIRRDLV 316

  Fly   320 SVVSSLAAS----------SAGSMNIERLDVKPPTPIPVSVATIISATTTKSQAQSLGQSKGQNS 374
            ::.:||.:.          |.|... |:|::...:.:.:          |:.|..:.....|...
Mouse   317 ALPASLISQIGYRCHPKLYSEGDPG-EKLELVAGSGVYI----------TRGQLMNCHLCAGVKH 370

  Fly   375 R--------------RESNSKGNRTKSSAS-RSRKSSGLQVAKAPVPAAQLDLTAAATPSITSSK 424
            :              ..:||.|...:||.| .|||....:|..|.....|     ...||...|:
Mouse   371 KVLLRRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLYCQ-----NFAPSFKESE 430

  Fly   425 F-IIDVASCDGPVRFR-RILNTAYGHKPEAMES-NALAGPATA-----PAGGSSNSTISEQ---- 477
            . :|....|....|.| |.|.......||.:|. .::.|.:.|     |...|:...:.||    
Mouse   431 MNVIAADMCTNARRVRKRWLPKIKSMLPEGVEMYRSVMGASAASLPLDPEFPSAAPQVFEQRIYA 495

  Fly   478 -HRSQQSVSLSFHQQMARAISSQQRQLSHQQQEESENSGDAIPATIGKQH--ATGATA--ASSAM 537
             .||..:..::..........|.....:.:..||.:..|..|......:.  |.|.::  |....
Mouse   496 ERRSDAATIVALRTDAVNVDLSTSANPAFEANEEVDGGGSVIQEVAAPEQLPADGQSSPQAFEQG 560

  Fly   538 STSSTH-----AGSNRKSQATGTGT 557
            :|||:.     |.:.|:.:.|..||
Mouse   561 NTSSSRPQTPVATATRRPEGTYAGT 585

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15725NP_572823.1 BTB_POZ 49..187 CDD:453885 22/135 (16%)
PRK14959 <192..>272 CDD:184923 25/125 (20%)
ZnF_C2H2 573..595 CDD:197676
Nacc2NP_080771.3 BTB_POZ_BTBD14A_NAC2 1..131 CDD:349598 21/134 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 177..196 2/18 (11%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 236..272 8/36 (22%)
BEN 371..448 CDD:214981 19/81 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..586 11/44 (25%)
Blue background indicates that the domain is not in the aligned region.

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