DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15725 and bach2b

DIOPT Version :9

Sequence 1:	NP_572823.1	Gene:	CG15725 / 32224	FlyBaseID:	FBgn0030417	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	XP_005160605.1	Gene:	bach2b / 555350	ZFINID:	ZDB-GENE-041001-139	Length:	823	Species:	Danio rerio

Alignment Length:	512	Identity:	104/512 - (20%)
Similarity:	182/512 - (35%)	Gaps:	148/512 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 TTASGELLLYL-SNVTADQFAPLLTYMYTGYLDLNVDNIFAVLLATHVLHMPRALEICRSFL--- 187
            |....:|:|.: ..|:|..|||||.:.||..|.|:.:||..|:.....|.|....:.|..||
Zfish    94 TQTDNDLVLSMPEEVSARGFAPLLQFAYTAKLLLSRENIQEVIRCAEFLRMHNLEDSCFRFLEAQ 158

  Fly   188 ARAQTEGY-----------------------------LNGNPAAQLCPVPSIPAKII----RPIP 219
            .|::.:|.                             |.|:|.::||      |:.:    ||..
Zfish   159 LRSEEDGLLLCRKMASESNHSEDEGMQPELLTTTAVTLPGSPRSRLC------AEALHSLRRPDH 217

  Fly   220 SK-ATMPNF----------GFLPLPQAPP----SVA---PSAQPTAHQPTTGIAPVASASILSSF 266
            .: |...:|          |...||:.|.    .:|   .:...::|..|:|..        |:|
Zfish   218 EQLAGTEDFTDGPMDFERHGTSDLPRCPKYRKYQLACNKHNNDASSHTSTSGFP--------STF 274

  Fly   267 GTNTQHMEHMEQPIAM---LDNEVDEEDVEVFIDSNTVTDNEAEELEPDVDMDCNVSVVSSLAAS 328
                   :.|.:|..|   .:...:||.:.:.:..|...|.|.::: .::|:|.:::|......|
Zfish   275 -------KEMSRPAVMQIKQEPRSEEESISLCLSGNEQEDGEKDDV-AEMDLDGSITVDQPKGRS 331

  Fly   329 SAGSMNIERLDVK--PPTPIPVSVATIISATTTKSQAQSLGQSKGQNSRRESNSKGNRTKSSASR 391
            .:.:. :..|..|  |.||..:....:|:       ||..|.::|.:.:....|.||
Zfish   332 KSPTC-LRALFKKDLPSTPQQLLANRLIN-------AQDKGTTQGDHKKDYRPSLGN-------- 380

  Fly   392 SRKSSGLQVAKAPVPAAQLDLTAAATPSITSSKFIIDVASCDG-------PVRFRRILNTAYGHK 449
                      :..:|.|....|....|.::     :...||||       |.|...|.::.
Zfish   381 ----------EFGMPVAFPKDTDGFPPGLS-----LKSPSCDGVCKQEVEPDRRSVIFSSG---- 426

  Fly   450 PEAMESNALAGPA-TAPAGGSSNSTISEQHRSQ-----QSVSLSFHQQMARAISSQQRQLSHQQQ 508
                ..:.|..|. :.|:|.|....:|| |..:     .|.||...|..:.:.::....|..:|:
Zfish   427 ----ACDRLGTPTHSHPSGNSLEKELSE-HMPKGLWAGASQSLPSSQTYSPSTTASDPPLLCRQR 486

  Fly   509 EESENSGDAIPATIGKQHATGATAASSAMSTSSTHAGSNRKSQATGTGTGSGSATAS 565
               .|:...:|..:..:.....|...::.|.||.....:          |||.:..|
Zfish   487 ---PNTSCPVPIKVCPRSPPSETRTRTSSSCSSYSYAED----------GSGGSPCS 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15725	NP_572823.1	BTB	49..189	CDD:197585	22/65 (34%)
		BTB	49..187	CDD:279045	20/60 (33%)
		zf-C2H2	573..595	CDD:278523
bach2b	XP_005160605.1	BTB	53..155	CDD:279045	20/60 (33%)
		BTB	64..159	CDD:197585	22/64 (34%)
		bZIP_BACH	631..701	CDD:269867
		coiled coil	635..697	CDD:269867
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46105
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100