Protein Alignment CG15725 and ZBTB7C

DIOPT Version :9

• Sequence 1: NP_572823.1
• Gene: CG15725 / 32224
• FlyBaseID: FBgn0030417
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: XP_016881094.1
• Gene: ZBTB7C / 201501
• HGNCID: 31700
• Length: 668
• Species: Homo sapiens
• Alignment Length: 709
• Identity: 124/709 - (17%)
• Similarity: 201/709 - (28%)
• Gaps: 287/709 - (40%)

  Fly    39 ATALVMSSPPDVILEVGPAPSNVRFVAHSLVLGMHSGYLRSAIR-LDETAAGTAASVSASASISI 102
            |.|..|::..|.::.: |.|::...|..||....|.|.|...:. :.|....|..||
Human    45 ALAENMANDIDELIGI-PFPNHSSEVLCSLNEQRHDGLLCDVLLVVQEQEYRTHRSV-------- 100

  Fly   103 TGATAASCNPSSSSSAASSSSSAVTTASGELLLYLSNVTADQFAPLLTYMYTGYLDLNVDNIFAV 167
                .|:|     |.......:|.|.||...:..:..|..:..|.:|.:.||..|.:...|:
Human   101 ----LAAC-----SKYFKKLFTAGTLASQPYVYEIDFVQPEALAAILEFAYTSTLTITAGNV--- 153

  Fly   168 LLATHVLHMPRALEI-CRSFLARAQTEGYLNGNPAAQLCPVPSIPAKIIRPIPSKATMPNFGFLP 231
               .|:|:..|.||| |                       :.::..:|:.|
Human   154 ---KHILNAARMLEIQC-----------------------IVNVCLEIMEP-------------- 178

  Fly   232 LPQAPPSVAPSAQPTAHQPTTGIAPVASASILSSFGTNTQHMEHMEQPIAMLDNEVDEEDVEVFI 296
                                               |.:....:         |.|.|::|.:
Human   179 -----------------------------------GGDGGEED---------DKEDDDDDED--- 196

  Fly   297 DSNTVTDNEAEELEPDVDMDCNVSVVSSLAASSAGSMNIERLDVKPPTPIPVSVATIISATTTKS 361
            |.:...:.|.||.|.|.|.|         ....|...|:       |.|      ..||...:.|
Human   197 DDDEEDEEEEEEEEEDDDDD---------TEDFADQENL-------PDP------QDISCHQSPS 239

  Fly   362 QAQSLGQSKGQNSRR------ESNSKGN----RTKSSASRSRKSSGLQVAKAPVPAAQLDLTAAA 416
            :...|.:....::.|      ::.|.|:    |..|..|..|::   ...||.:|..:..|:..|
Human   240 KTDHLTEKAYSDTPRDFPDSFQAGSPGHLGVIRDFSIESLLREN---LYPKANIPDRRPSLSPFA 301

  Fly   417 T---PSITSSKF---------IIDVASCDGPVRFRRILNTAYGHKPEAMESNALAGPATAP---- 465
            .   |.:....|         .:|....|..::.|:|       |.|  |...|..|...|
Human   302 PDFFPHLWPGDFGAFAQLPEQPMDSGPLDLVIKNRKI-------KEE--EKEELPPPPPPPFPND 357

  Fly   466 ---------AGGSSNSTISEQHRSQQSVSLSF----------------HQQMARAISSQQRQLSH 505
                     .||......:|   :.....|:|                .::..:..:|||..:.|
Human   358 FFKDMFPDLPGGPLGPIKAE---NDYGAYLNFLSATHLGGLFPPWPLVEERKLKPKASQQCPICH 419

  Fly   506 QQQEESENSGDAIPATIGKQHATGATAASSAMSTSSTHAGSNRKSQATGTGTGSGSATASSAGNQ 570
            :             ..:|                    ||...:...|.||             :
Human   420 K-------------VIMG--------------------AGKLPRHMRTHTG-------------E 438

  Fly   571 ELYVCVYCKHTFKSQYCYQKHAKRHLNPLTLTTNDKKLLMESAASMANTIEMDNPSSVGQSGANN 635
            :.|:|..|:..|..|...:.|.::|      |.....|.:...|...:..::.|..
Human   439 KPYMCTICEVRFTRQDKLKIHMRKH------TGERPYLCIHCNAKFVHNYDLKNHM--------- 488

  Fly   636 SSGSIATGNGATAVAATTALLRREVRPLDMNVQYYPCKTCGSKFPSYYFVHKH--RKMC 692
               .|.||                |||       |.|:.|...|.....:|:|  |:.|
Human   489 ---RIHTG----------------VRP-------YQCEFCYKSFTRSDHLHRHIKRQSC 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15725	NP_572823.1	BTB	49..189	CDD:197585	34/141 (24%)
		BTB	49..187	CDD:279045	34/139 (24%)
		zf-C2H2	573..595	CDD:278523	6/21 (29%)
ZBTB7C	XP_016881094.1	BTB	73..176	CDD:279045	29/148 (20%)
		BTB	84..177	CDD:197585	26/138 (19%)
		C2H2 Zn finger	415..435	CDD:275368	4/52 (8%)
		zf-H2C2_2	430..452	CDD:290200	7/34 (21%)
		C2H2 Zn finger	443..463	CDD:275368	5/19 (26%)
		zf-H2C2_2	456..480	CDD:290200	5/29 (17%)
		C2H2 Zn finger	471..491	CDD:275368	2/31 (6%)
		zf-H2C2_2	483..508	CDD:290200	11/59 (19%)
		C2H2 Zn finger	499..517	CDD:275368	5/17 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46105
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100