DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15725 and NACC2

DIOPT Version :10

Sequence 1:NP_572823.1 Gene:CG15725 / 32224 FlyBaseID:FBgn0030417 Length:745 Species:Drosophila melanogaster
Sequence 2:NP_653254.1 Gene:NACC2 / 138151 HGNCID:23846 Length:587 Species:Homo sapiens


Alignment Length:476 Identity:90/476 - (18%)
Similarity:149/476 - (31%) Gaps:169/476 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    63 FVAHSLVLGMHSGYLRSAIRLDETAAGTAASVSASASISITGATAASCNPSSSSSAASSSSSAVT 127
            |.||..||...|.|.|...           |.::.::..:.|:...:|                 
Human    41 FKAHRAVLAASSLYFRDLF-----------SGNSKSAFELPGSVPPAC----------------- 77

  Fly   128 TASGELLLYLSNVTADQFAPLLTYMYTGYLDLNVDNIFAVLLATHVLHMPRALE----------- 181
                             |..:|::.|||.|.:.......|:.....|.:...:|           
Human    78 -----------------FQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDLMFKVSS 125

  Fly   182 -ICRSFLARAQTEGYLNGNPAAQLCPV----------PSIPAKIIRPIPSKATMPNFGFLPLPQA 235
             .|.|..|..:..|....:|..||.|.          ||:|..::..:..:|       :.||.|
Human   126 PHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVKHEA-------MELPPA 183

  Fly   236 PPSVAPSAQPTAHQPTTGIAPVASASI----------------LSSFGTNTQHMEHMEQP----- 279
            .|.:||. :|....|..|:|..|.|::                :.|..|....::.|..|     
Human   184 GPGLAPK-RPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMPYPQGERT 247

  Fly   280 ------IAMLD------NEVDEEDVEVFIDSNTVTDNEAEELEPDVDMDCNVSVVSSLAASSAGS 332
                  :...|      ||.||||.|.:       |...||            ....:...::||
Human   248 SPGASSLPTTDSPTSYHNEEDEEDDEAY-------DTMVEE------------QYGQMYIKASGS 293

  Fly   333 MNIERLDVKPPTPIPV-SVATIISATTTKSQAQSLGQSKGQNSRRESNSKGNRTKSSASRSRKSS 396
            ..::    :.|.|:|: |.:.::......:...||....|.....:..|:|:             
Human   294 YAVQ----EKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGD------------- 341

  Fly   397 GLQVAKAPVPAAQLDLTAAATPSITSSKFIIDVASCDG---PVRFRRILNTAYGHKPEAMESNAL 458
                     |..:|:|.|.:...||..: :::...|.|   .|..||:|.|.:       :.|.|
Human   342 ---------PGEKLELVAGSGVYITRGQ-LMNCHLCAGVKHKVLLRRLLATFF-------DRNTL 389

  Fly   459 AGPATAPAGGSSNSTISEQHR 479
            |.    ..|....|:.|:..|
Human   390 AN----SCGTGIRSSTSDPSR 406

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15725NP_572823.1 BTB_POZ 49..187 CDD:453885 22/135 (16%)
PRK14959 <192..>272 CDD:184923 23/105 (22%)
ZnF_C2H2 573..595 CDD:197676
NACC2NP_653254.1 BTB_POZ_BTBD14A_NAC2 1..131 CDD:349598 21/134 (16%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 240..272 7/31 (23%)
BEN 373..450 CDD:214981 12/45 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 542..587
Blue background indicates that the domain is not in the aligned region.

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