DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15725 and Bach2

DIOPT Version :9

Sequence 1:	NP_572823.1	Gene:	CG15725 / 32224	FlyBaseID:	FBgn0030417	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	XP_006537629.1	Gene:	Bach2 / 12014	MGIID:	894679	Length:	846	Species:	Mus musculus

Alignment Length:	569	Identity:	109/569 - (19%)
Similarity:	169/569 - (29%)	Gaps:	210/569 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 DVILEVGPAPSNVRFVAHSLVLGMHSGYLRSAIRLDETAAGTAASVSASASISITGATAASCNPS 113
            |::.:|........|.||..||...|.|...|:
Mouse    41 DILCDVTLIVERKEFRAHRAVLAACSEYFWQAL-------------------------------- 73

  Fly   114 SSSSAASSSSSAVTTASGELLLYL-SNVTADQFAPLLTYMYTGYLDLNVDNIFAVLLATHVLHMP 177
                        |.....:|::.| ..|||..|.|||.:.||..|.|:.:||..|:.....|.|.
Mouse    74 ------------VGQTKDDLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIREVIRCAEFLRMH 126

  Fly   178 RALEICRSFLARAQTEGYLN---------------------GNPAA------------------- 202
            ...:.|.|||   ||: .||                     ||.|.
Mouse   127 NLEDSCFSFL---QTQ-LLNREDGLFVCRKDSACQRPQEDHGNSAGEEEEEEETMDSETARMACA 187

  Fly   203 --QLCPVP-SIPAKIIRPIPSKATMPNFGFLPLPQAPPSVAPSAQPTA----------------- 247
              |:.|.| |..|..| |:..|..    ..||..:.|.....:::..|
Mouse   188 TDQMLPDPISFEATAI-PVAEKEE----ALLPESEVPTDTKENSEKGALTQYPRYKKYQLACTKN 247

  Fly   248 --HQPTTGIAPVASASILSSFGTNTQHMEHM-----EQPIAMLDNEVDEEDVEVFIDSNTVTDNE 305
              ..|:.|.:..||.....|.|.:.:....|     |.|    ..|.:||.:.:.:..:   :.:
Mouse   248 VYSAPSHGTSGFASTFSEDSPGNSLKPGLPMGQIKSEPP----SEETEEESITLCLSGD---ETD 305

  Fly   306 AEELEPDVDMDCNVSVVSSLAASSAGSMNIERLDVKPPTPIPVSVATIISATTTKSQAQS----- 365
            .::...||:|                       |.|.|:|.|.......:|...:|::.|
Mouse   306 IKDRPGDVEM-----------------------DRKQPSPAPTPSTPTGAACLDRSRSVSSPSCL 347

  Fly   366 ---LGQSKG-QNSRRESNSKGNRTKSSASRSRKSSGLQVAKAPVPAAQLDLTAAATPSITSSKFI 426
               .|.:|| :::...|.|:....:|||....|.           .:|.||....||
Mouse   348 RSLFGITKGVESTGLPSTSQQPLVRSSACPFNKG-----------ISQGDLKTDYTP-------- 393

  Fly   427 IDVASCDGPVRFRRILNTAYG--HKPEAMESNALAGPATAPAGGSSNSTISEQHRSQQSVSLSFH 489
                           |...||  |..:...||...|   :|..|....|:.:|.......|:.|.
Mouse   394 ---------------LAGNYGQPHVGQKDVSNFAMG---SPLRGPGPETLCKQEGELDRRSVIFS 440

  Fly   490 QQMA----------RAISSQQRQLSHQQQEES-ENSGDAIPATIGKQHA 527
            ....          .|:|:..:.||....:.. ..:|.::|::....|:
Mouse   441 ASACDQPNTPVHSYSAVSNLDKDLSEPVPKSLWVGAGQSLPSSQAYSHS 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15725	NP_572823.1	BTB	49..189	CDD:197585	33/140 (24%)
		BTB	49..187	CDD:279045	31/138 (22%)
		zf-C2H2	573..595	CDD:278523
Bach2	XP_006537629.1	BTB_POZ_BACH2	13..136	CDD:349587	31/138 (22%)
		bZIP_BACH	646..716	CDD:269867
		coiled coil	655..706	CDD:269867
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46105
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100