DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15725 and LOC103910274

DIOPT Version :9

Sequence 1:	NP_572823.1	Gene:	CG15725 / 32224	FlyBaseID:	FBgn0030417	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	XP_009297857.1	Gene:	LOC103910274 / 103910274	-ID:	-	Length:	563	Species:	Danio rerio

Alignment Length:	659	Identity:	113/659 - (17%)
Similarity:	208/659 - (31%)	Gaps:	227/659 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 FVAHSLVLGMHSGYLRSAIRLDETAAGTAASVSASASISITGATAASCNPSSSSSAASSSSSAVT 127
            |.||..||...|.|.|...                                 :|||.|.:.:.|.
Zfish    41 FKAHRAVLAASSSYFRDLF---------------------------------NSSAGSKTPTVVE 72

  Fly   128 TASGELLLYLSNVTADQFAPLLTYMYTGYLDLNVDNIFAVLLATHVLHMPRALEICRSFLARAQT 192
            ....        |....|..:|.:.|||.|.:||.:.|.::.....|.:.:.:|....|..:..:
Zfish    73 LPPA--------VQPQSFQQILAFCYTGRLSMNVGDQFLLMYTAGFLQIQQIMEKGTEFFLKVSS 129

  Fly   193 EGYLNGNPAAQLCPVPSIPAKIIRPIPSKATMPNFGFLPLPQAPPSVAPSAQPTAHQPTTGIAPV 257
                           ||..::               .|...:.|||   ..|....|...|.|..
Zfish   130 ---------------PSCDSQ---------------GLHTEETPPS---EPQSPVTQTAAGAAAN 161

  Fly   258 ASASILSSFGTNTQHMEHMEQPIAMLDNEVDEEDVEVFIDSNTVTDNEAEELEPDVDMDCNVSVV 322
            ..|.:::                                   |.....|..|.|       :.:|
Zfish   162 GGAGVVA-----------------------------------TAASRPASCLTP-------LPLV 184

  Fly   323 SSLAASSAGSMNIERLDVKPPTPIPVSVATIISATTTKSQAQSLGQSKGQNSRR-----ESNSKG 382
            |        .:..|:.:..|.:.:...||..:...:.:..:..||.:.|...|:     :..::|
Zfish   185 S--------RVKTEQPETSPYSVVCTPVAKRLWEGSNREGSGGLGAAGGGGMRKAARFSQEMARG 241

  Fly   383 NRTKSSASRSRKSSGLQVAK----APVPAAQLDLTAAATPSITSSKFIIDVASCDGPV------- 436
            :..:...|......||.:..    |...:...:.|::|||..||...:...|| |.|:
Zfish   242 SAIQQQGSMGGLGMGLGMGTGGHGAGSGSTNGNGTSSATPEGTSPGTLSAYAS-DSPISYHDDEE 305

  Fly   437 -----------RFRRILN--TAY---------GHKPEAMESNALAGPATAPAGGSSNSTISEQHR 479
                       ::|:|.|  |.|         |.:.||:..::...|               :.|
Zfish   306 EEEAVDDGTEEQYRQICNMYTMYSMLNVGATAGERVEALPDHSETRP---------------RMR 355

  Fly   480 SQQSVSLSFHQQMARAISSQQRQLSHQQQEESEN----SGDAIPATIGKQHATGATAASSAMSTS 540
            .:|.:: |...::...|.::.....:::.:.:|.    ||.::       :.:.|...:..:|..
Zfish   356 GRQDLA-SLPAELIAQIGNRCHPKLYEEGDPAEKLELVSGTSV-------YISRAQLMNCHVSAG 412

  Fly   541 STH---------AGSNRKSQATGTGTGSGSATASSA----GNQELY-VCVYCKHTFKSQYCYQKH 591
            :.|         |..:|.:.|...|||..|:|...:    .::.|: |..||:: |.:.:   |.
Zfish   413 TRHKVLLRRLLAAFFDRSTLANSCGTGIRSSTNDPSRKPLDSRVLHAVKFYCQN-FATSF---KE 473

  Fly   592 AKRHLNPLTLTTNDK-----------KLLMESAASMA------NTIEMDNPSS--VGQSGANNSS 637
            ::.:.....:.||.:           ||||....:.|      |.:|.|..|.  ..::.:....
Zfish   474 SEMNAIAADMCTNARRVVRKSWIPKLKLLMAEGDAYASFLPDSNKMEADGLSGEPTFETASLEGG 538

  Fly   638 GSIATGNGA 646
            .|:.||..:
Zfish   539 ASVETGGSS 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15725	NP_572823.1	BTB	49..189	CDD:197585	26/125 (21%)
		BTB	49..187	CDD:279045	25/123 (20%)
		zf-C2H2	573..595	CDD:278523	5/22 (23%)
LOC103910274	XP_009297857.1	BTB	20..125	CDD:279045	26/124 (21%)
		BTB	31..126	CDD:197585	26/125 (21%)
		BEN	416..494	CDD:214981	16/81 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46105
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100