Protein Alignment Tis11 and CTH1

DIOPT Version :9

• Sequence 1: NP_001259490.1
• Gene: Tis11 / 32222
• FlyBaseID: FBgn0011837
• Length: 436
• Species: Drosophila melanogaster
• Sequence 2: NP_010435.1
• Gene: CTH1 / 851729
• SGDID: S000002558
• Length: 325
• Species: Saccharomyces cerevisiae
• Alignment Length: 274
• Identity: 73/274 - (26%)
• Similarity: 109/274 - (39%)
• Gaps: 54/274 - (19%)

  Fly     5 ILQKSREQDDSHYFERGDISKYVTMNDH-----------------LGDF------DCNEVRK-EI 45
            :|.::.:.|||...|..:|::...::::                 ||||      |...... .|
Yeast    50 LLNENTDNDDSSSSEGHNINETDILSEYSPRPSPWLPSKPNCYHPLGDFKDLIISDSRPTNTLPI 114

  Fly    46 RMLLAHGANLDQQHQQQPHRHHGGL---------TRTISQPAQLIQQQQQQHQQQQQQQPAVASL 101
            ....|...|:......:..|....|         |...|.|  |..:..|:..|...|...:...
Yeast   115 NNPFAGNNNISTLATTEKKRKKRSLEVEINPTYTTSAFSLP--LTAENLQKLSQVDSQSTGLPYT 177

  Fly   102 VTITENLGNMNLHRKLERTQSEPLPPQQPMNTSRYKTELCRPFEEAGECKYGEKCQFAHGSHELR 166
            :.|.:.       .|||..:..||...|.:|.:.||||||..|...|.||||.|||||||.:||:
Yeast   178 LPIQKT-------TKLEPCRRAPLQLPQLVNKTLYKTELCESFTIKGYCKYGNKCQFAHGLNELK 235

  Fly   167 NVHRHPKYKTEYCRTFHSVGFCPYGPRCHFVH----------NADEARAQQAAQAAKSSTQSQSQ 221
            ...:...|:|:.|..:..:|:||||.||.|.|          ||::.|::..|.....:  |.:.
Yeast   236 FKKKSNNYRTKPCINWSKLGYCPYGKRCCFKHGDDKDVEIYQNANDGRSKDTALTPLPT--SLAP 298

  Fly   222 SQQSSSQNFSPKSN 235
            |...:..|.|...|
Yeast   299 SNNDNITNLSKPRN 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_001259490.1	zf-CCCH	136..161	CDD:279036	17/24 (71%)
		zf-CCCH	174..198	CDD:279036	11/23 (48%)
CTH1	NP_010435.1	CTH1	1..323	CDD:227395	73/274 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I3017
eggNOG	1	0.900	-	-		E1_COG5063
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000616
OrthoInspector	1	1.000	-	-		otm46769
orthoMCL	1	0.900	-	-		OOG6_101179
Panther	1	1.100	-	-	LDO	PTHR12547
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2078
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.800