DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tis11 and AT1G04990

DIOPT Version :9

Sequence 1:	NP_001259490.1	Gene:	Tis11 / 32222	FlyBaseID:	FBgn0011837	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_001318923.1	Gene:	AT1G04990 / 839351	AraportID:	AT1G04990	Length:	404	Species:	Arabidopsis thaliana

Alignment Length:	160	Identity:	40/160 - (25%)
Similarity:	58/160 - (36%)	Gaps:	40/160 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 LHRKLERTQSEPLPPQQPMNTSRYKTELCRPFEEAGECKYGEKCQFAHGSHELRNVHRHPKYKTE 177
            |:|.|..:..:|               .||.|...|.||||:.|:::|..  :|.....|.....
plant   254 LNRGLSESSDQP---------------ECRFFMNTGTCKYGDDCKYSHPG--VRISQPPPSLINP 301

  Fly   178 Y----------CRTFHSVGFCPYGPRCHFVHNADEARAQQAAQAAKSSTQSQSQSQQSSSQNFSP 232
            :          |..|.|.|||.:||.|.|    |............:|..:...|..::.|..||
plant   302 FVLPARPGQPACGNFRSYGFCKFGPNCKF----DHPMLPYPGLTMATSLPTPFASPVTTHQRISP 362

  Fly   233 KSNQSSNQS-SN--------SSSSSSSSGG 253
            ..|:|.::| ||        ||.:.....|
plant   363 TPNRSDSKSLSNGKPDVKKESSETEKPDNG 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_001259490.1	zf-CCCH	136..161	CDD:279036	9/24 (38%)
Tis11	NP_001259490.1	zf-CCCH	174..198	CDD:279036	10/33 (30%)
AT1G04990	NP_001318923.1	zf-CCCH	48..73	CDD:395517
		zf-CCCH	92..117	CDD:395517
		zf-CCCH	137..162	CDD:395517
		YTH1	<261..403	CDD:227416	37/153 (24%)
		zf-CCCH	263..287	CDD:395517	10/38 (26%)
		zf-CCCH	308..334	CDD:395517	11/29 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5063
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770