DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tis11 and AT3G48440

DIOPT Version :9

Sequence 1:	NP_001259490.1	Gene:	Tis11 / 32222	FlyBaseID:	FBgn0011837	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_190414.1	Gene:	AT3G48440 / 824003	AraportID:	AT3G48440	Length:	448	Species:	Arabidopsis thaliana

Alignment Length:	411	Identity:	86/411 - (20%)
Similarity:	129/411 - (31%)	Gaps:	123/411 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LQKSREQDDSHYFERGDISKYV-TMNDHLGDFDCNEVRKEIRMLLAHGANLDQQHQQQPHRHHGG 69
            :.:|...|.||.....|::... .::|.|.:...|||.||           ..:........:||
plant    16 VSRSYSGDSSHDRSLSDLNHAAEDLSDKLKNVGLNEVTKE-----------QSEKMMSVSESNGG 69

  Fly    70 LTRTISQPAQLIQQQQQQHQQQQQQQPAVASLVTITENLGNMNLHRKLERTQSEPLPPQQPMNTS 134
            |.   |.....|.|::::.:                |:.............:||.:.|.:|
plant    70 LD---SNAVVTINQEEEEEE----------------EDRDGYGYGDGWSENESENVYPVRP---- 111

  Fly   135 RYKTELCRPFEEAGECKYGEKCQFAHGSHELRNVHRHPKYKTEY----------CRTFHSVGFCP 189
              ..|.|..:...|.||:|..|:|.|.......:.|..|.:.:.          |:.:...|.|.
plant   112 --GAEDCSFYMRTGSCKFGSSCKFNHPLARKFQIARDNKVREKEDDGGKLGLIDCKYYFRTGGCK 174

  Fly   190 YGPRCHFVHNADEARAQQAAQAAKSSTQSQSQSQQSSSQNF-----SPKSNQSSNQSSNSS---- 245
            ||..|.|.|...::....|.:.                 ||     .|...:......|.|
plant   175 YGETCRFNHTIPKSGLASAPEL-----------------NFLGLPLRPGEVECPYYMRNGSCKYG 222

  Fly   246 -----SSSSSSGGGGGGGNSINNNNGSQFYLPLSPPL-----SMSTGSDRE----SPTGSLSLSP 296
                 :....:..||....|...|||.... ..||..     |.|..|.|.    ||...:.||.
plant   223 AECKFNHPDPTTIGGTDSPSFRGNNGVSIG-TFSPKATFQASSTSWSSPRHVNGTSPFIPVMLSQ 286

  Fly   297 TNSLTSFPFHDALQHGYLAS-----NGAKS-------NSSASSTSSASGMGLGMSMGIGQGMIIG 349
            |:.:||   .:...:||.||     .|..|       |:|::.||                |::.
plant   287 THGVTS---QNPEWNGYQASVYSSERGVFSPSTTYLMNNSSAETS----------------MLLS 332

  Fly   350 QGLGMGHHGPATP-PESPNVP 369
            |   ..|..||.. ||.|:.|
plant   333 Q---YRHQMPAEEFPERPDQP 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_001259490.1	zf-CCCH	136..161	CDD:279036	8/24 (33%)
Tis11	NP_001259490.1	zf-CCCH	174..198	CDD:279036	7/33 (21%)
AT3G48440	NP_190414.1	zf-CCCH	111..136	CDD:279036	9/30 (30%)
		zf-CCCH	164..183	CDD:279036	7/18 (39%)
		zf-CCCH	205..231	CDD:279036	3/25 (12%)
		zf-CCCH	347..373	CDD:279036	2/4 (50%)
		zf-CCCH	393..419	CDD:279036
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5063
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770