DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tis11 and HUA1

DIOPT Version :9

Sequence 1:	NP_001259490.1	Gene:	Tis11 / 32222	FlyBaseID:	FBgn0011837	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_187874.2	Gene:	HUA1 / 820448	AraportID:	AT3G12680	Length:	524	Species:	Arabidopsis thaliana

Alignment Length:	157	Identity:	37/157 - (23%)
Similarity:	59/157 - (37%)	Gaps:	36/157 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 QPAVASLVTITENLGNMNL-----HRKLERTQSEP-------LPPQQPMNTSRYKTELCRPFEEA 147
            |.|..:...::.|..|:||     .....:|.::|       ..||:|..:.      |..:.:.
plant   374 QAAGVNYSLVSSNTANLNLGLVTPATSFYQTLTQPTLGVISATYPQRPGQSE------CDYYMKT 432

  Fly   148 GECKYGEKCQFAHGSHEL----RNVHRHPKYKTEY-----------CRTFHSVGFCPYGPRCHFV 197
            ||||:||:|:|.|.:..|    :...:.|..|...           |..:...|.|.||..|.|.
plant   433 GECKFGERCKFHHPADRLSAMTKQAPQQPNVKLSLAGYPRREGALNCPYYMKTGTCKYGATCKFD 497

  Fly   198 H---NADEARAQQAAQAAKSSTQSQSQ 221
            |   ....|:....|.||.::....:|
plant   498 HPPPGEVMAKTTSEADAAGATNTDTTQ 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_001259490.1	zf-CCCH	136..161	CDD:279036	9/24 (38%)
Tis11	NP_001259490.1	zf-CCCH	174..198	CDD:279036	8/34 (24%)
HUA1	NP_187874.2	zf-CCCH	342..367	CDD:395517
		zf-CCCH	421..446	CDD:395517	10/30 (33%)
		zf-CCCH	478..500	CDD:395517	8/21 (38%)
		zf-CCCH	176..200	CDD:395517
		zf-CCCH	226..252	CDD:395517
		zf-CCCH	274..295	CDD:395517
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5063
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770