DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tis11 and CZF1

DIOPT Version :9

Sequence 1:	NP_001259490.1	Gene:	Tis11 / 32222	FlyBaseID:	FBgn0011837	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_001031517.1	Gene:	CZF1 / 818605	AraportID:	AT2G40140	Length:	597	Species:	Arabidopsis thaliana

Alignment Length:	412	Identity:	98/412 - (23%)
Similarity:	141/412 - (34%)	Gaps:	136/412 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 NEVRKEIRMLLA--HGANLDQQHQQQPHRHHGGLTRTISQPAQLIQQQQQQHQQQQQQQPAVASL 101
            |:.||.:.:||.  ||:                          ::::::::.:....:.||.|||
plant   164 NQSRKAVEVLLTGIHGS--------------------------VMEEEEEELKSVVTKYPADASL 202

  Fly   102 VTITENLGNMNLHRKL-------ERTQSE---PLPPQQPMNTSR--------YKTELCRPFEEAG 148
            ..|.|.:...:..|..       .|..|.   ..|...|...:|        |....|..|.: |
plant   203 PDINEGVYGTDDFRMFSFKVKPCSRAYSHDWTECPFVHPGENARRRDPRKYPYTCVPCPEFRK-G 266

  Fly   149 ECKYGEKCQFAHGSHELRNVHRHP-KYKTEYCRTFHSVGFCPYGPRCHFVHNADEARAQQAAQAA 212
            .|..|:.|::|||..|   ...|| :|:|..|:  ...| |.... |.|.|..||.|...|
plant   267 SCPKGDSCEYAHGVFE---SWLHPAQYRTRLCK--DETG-CARRV-CFFAHRRDELRPVNA---- 320

  Fly   213 KSSTQSQSQSQQSSSQNFSPKSNQSSNQSSNSSSSSSSSGGGGGGGNSINNNNGSQFYLPLSPPL 277
              ||.|...|.:||:|  ||:.:..|..:..||..:|....|                :||||
plant   321 --STGSAMVSPRSSNQ--SPEMSVMSPLTLGSSPMNSPMANG----------------VPLSP-- 363

  Fly   278 SMSTGSDRESPTGSLSLSPTNSLTSFPFHDALQHGYLASNGAKSNSSASSTSSASGMGLGMSMGI 342
                      ..|.|..:..||||..|         |..||    |...||.||..|.:.|.:..
plant   364 ----------RNGGLWQNRVNSLTPPP---------LQLNG----SRLKSTLSARDMDMEMELRF 405

  Fly   343 GQGMIIGQGLGMGHHGPATPP-----------------ESP-------NVPISPVHTPPPYDVVV 383
                   :||.....|...|.                 :||       :.|.|||..|||:....
plant   406 -------RGLDNRRLGDLKPSNLEETFGSYDSASVMQLQSPSRHSQMNHYPSSPVRQPPPHGFES 463

  Fly   384 SGS-GAGNNSVGSKQLLQKSVS 404
            |.: .|...:..|....::|:|
plant   464 SAAMAAAVMNARSSAFAKRSLS 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_001259490.1	zf-CCCH	136..161	CDD:279036	8/24 (33%)
Tis11	NP_001259490.1	zf-CCCH	174..198	CDD:279036	7/23 (30%)
CZF1	NP_001031517.1	Ank_2	<76..145	CDD:403870
		ANK repeat	76..109	CDD:293786
		ANK repeat	111..145	CDD:293786
		ZnF_C3H1	258..279	CDD:214632	7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	48	1.000	Inparanoid score	I2649
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	2.010