Protein Alignment Tis11 and zfp36l1

DIOPT Version :10

• Sequence 1: NP_511141.2
• Gene: Tis11 / 32222
• FlyBaseID: FBgn0011837
• Length: 436
• Species: Drosophila melanogaster
• Sequence 2: NP_001072758.1
• Gene: zfp36l1 / 780215
• XenbaseID: XB-GENE-966625
• Length: 345
• Species: Xenopus tropicalis
• Alignment Length: 377
• Identity: 124/377 - (32%)
• Similarity: 171/377 - (45%)
• Gaps: 107/377 - (28%)

  Fly    63 PHRHHGGLTRTISQPAQLIQQQQQQHQQQQQQQPAVASLVTITENLGNMNLHRKLERTQSEP--- 124
            |.||      :::.|.  .:..|.|.....:.:|:.|        :||.. ::..:|:.||.
 Frog    55 PRRH------SVTLPN--AKFNQNQFLNSLKMEPSTA--------MGNKE-NKFRDRSFSENGER 102

  Fly   125 --LPPQQPMNTSRYKTELCRPFEEAGECKYGEKCQFAHGSHELRNVHRHPKYKTEYCRTFHSVGF 187
              ..|...:|:|||||||||||||.|.||||:|||||||.||||::.||||||||.|||||::||
 Frog   103 LLQKPGGQVNSSRYKTELCRPFEENGSCKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGF 167

  Fly   188 CPYGPRCHFVHNADEARAQQAAQAAKSSTQSQSQSQQSSSQ-NFSPKSNQSSNQSSNSSSSSSSS 251
            |||||||||:|||:|.|.......|:.|..|.|:.::...| :||.....::|...:|.:|
 Frog   168 CPYGPRCHFIHNAEERRLVSGRDQAQFSLSSSSKMERPRLQHSFSFAGFPTTNGLLDSPTS---- 228

  Fly   252 GGGGGGGNSINNNNGSQFYLPLSPPLSMSTGSDRESPTGSLSLSPTNSLTSFPFHDALQHGYLAS 316
                                 ::||..:||.....|||     .|..|...|.|
 Frog   229 ---------------------ITPPPILSTDDLINSPT-----LPDCSSNPFTF----------- 256

  Fly   317 NGAKSNSSASSTSSASGMGLGMSMGIGQGMIIGQGLGMGHHGPAT-----PPESPNVPISPVHTP 376
               .|...||..:.:.||.|.:|.....|            .|.:     ..|||.:..||   |
 Frog   257 ---SSQELASLFAPSMGMQLPLSNSNAAG------------SPTSFLFRPMSESPQMFDSP---P 303

  Fly   377 PPYDVV------VSGSGAGNNSVGSKQLLQKSVSTPMQQEDTPRLPVFNRLS 422
            .|.|.:      :|.|.:|::|        .::.|      |.|||:|:|||
 Frog   304 SPQDSLSDQEGYLSSSSSGSDS--------PTLDT------TKRLPIFSRLS 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_511141.2	CTH1	<121..>198	CDD:227395	57/81 (70%)
zfp36l1	NP_001072758.1	Tis11B_N	1..104	CDD:461350	13/65 (20%)
		CTH1	<79..>178	CDD:227395	62/107 (58%)