DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tis11 and zfp36l2.2

DIOPT Version :9

Sequence 1:	NP_001259490.1	Gene:	Tis11 / 32222	FlyBaseID:	FBgn0011837	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	XP_012816715.1	Gene:	zfp36l2.2 / 733887	XenbaseID:	XB-GENE-5885707	Length:	289	Species:	Xenopus tropicalis

Alignment Length:	218	Identity:	70/218 - (32%)
Similarity:	96/218 - (44%)	Gaps:	43/218 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 PL-PPQQP----------------MNTSRYKTELCRPFEEAGECKYGEKCQFAHGSHELRNVHRH 171
            || ||..|                :::.|||||||..:.|:|.|.|..:||||||..|||...:|
Frog    27 PLSPPSDPEIPLLPSFSAPPKHLSLSSLRYKTELCTRYAESGFCAYRNRCQFAHGLSELRPPVQH 91

  Fly   172 PKYKTEYCRTFHSVGFCPYGPRCHFVHNADEARAQQAAQAA------KSSTQSQSQSQQSSSQNF 230
            ||||||.||:||.:|.|.||.||.|:|:..|.|....:..|      :.:...:.|.:...|...
Frog    92 PKYKTELCRSFHVLGTCNYGLRCLFIHSPQERREPPVSPDAPGLPTRRYAGPYREQCRLWRSPGG 156

  Fly   231 SPKSNQSSNQSSNSSSSSSSSGGGGGGGNSINNNNGSQFYLPLSPPLSM-------STGS----- 283
            .|...:...|.......:.......|     :...|::.:...||||..       |:||
Frog   157 CPYGARCHFQHPKGFREACRHFAAHG-----DCPYGARCHFSHSPPLDRWGSGTKNSSGSLSPSD 216

  Fly   284 -DRESPTGS--LSLSPTNSLTSF 303
             |.:|..|:  ||.||.|:..||
Frog   217 PDPDSDPGTPVLSESPANNAFSF 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_001259490.1	zf-CCCH	136..161	CDD:279036	14/24 (58%)
Tis11	NP_001259490.1	zf-CCCH	174..198	CDD:279036	15/23 (65%)
zfp36l2.2	XP_012816715.1	CTH1	<27..169	CDD:227395	51/141 (36%)
zfp36l2.2	XP_012816715.1	zf-CCCH	171..195	CDD:366217	2/28 (7%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12547
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X9434
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010