Protein Alignment Tis11 and Zfp36l2

DIOPT Version :9

• Sequence 1: NP_001259490.1
• Gene: Tis11 / 32222
• FlyBaseID: FBgn0011837
• Length: 436
• Species: Drosophila melanogaster
• Sequence 2: XP_008763271.1
• Gene: Zfp36l2 / 298765
• RGDID: 1308913
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 437
• Identity: 127/437 - (29%)
• Similarity: 170/437 - (38%)
• Gaps: 164/437 - (37%)

  Fly    72 RTISQPAQLIQQQQQQHQQQQQQQPAVASLVTITENLGNMNLHRKLERTQSEPLPPQQPMNTSRY 136
            |:.|:..:  :.|...|.||||:..:.:.:                              |::||
  Rat   132 RSFSENGE--RSQHLLHLQQQQKGGSGSQI------------------------------NSTRY 164

  Fly   137 KTELCRPFEEAGECKYGEKCQFAHGSHELRNVHRHPKYKTEYCRTFHSVGFCPYGPRCHFVHNAD 201
            ||||||||||:|.||||||||||||.||||::.||||||||.|||||::|||||||||||:||||
  Rat   165 KTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAD 229

  Fly   202 E------------ARAQQAAQAAKSSTQSQSQSQQSSSQNFS----------------------- 231
            |            .||..|..|.......:.:.:...|.:||
  Rat   230 ERRPAPSGGASGDLRAFGARDALHLGFAREPRPKLHHSLSFSGFPSGHHQPPGGLESPLLLDSPT 294

  Fly   232 ------PKSNQSSNQSSNSSSSSSSSGG-----------------------GGGGGNSINNNNGS 267
                  |..:.:|:.||::||.||:|..                       |.||...:
  Rat   295 SRTPPPPSCSSASSCSSSASSCSSTSAASTPSGAPTCCASAAAAAAAALLYGPGGAEDL------ 353

  Fly   268 QFYLPLSPPLSMSTGSDRESPTGSLSLSPTNSLTSFPFHDALQ-HGYLASNGAKSNSSASSTSSA 331
                 |:|....:|.|.......:.:..|..|....|.  |:| |.:.|:..|...|..
  Rat   354 -----LTPGAPCATCSTTSCANNAFTFGPELSSLITPL--AIQTHNFAAAAAAYYRSQQ------ 405

  Fly   332 SGMGLGMSMGIGQGMIIGQGLGMGHHGPATPPESPNVPI-------------SPVHTPPP----- 378
                              |||......||.||.:|..|.             |||...||
  Rat   406 ------------------QGLAGLAPAPAQPPAAPAPPSPPFGFQLPRRLSESPVFDAPPSPPDS 452

  Fly   379 ---YDVVVSGSGAGNNSVGSKQLLQKSVSTPMQQEDTPRLPVFNRLS 422
               .|..:|||.:..:..||:        :| ..:...|||:|:|||
  Rat   453 LSDRDSYLSGSLSSGSLSGSE--------SP-SLDPGRRLPIFSRLS 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_001259490.1	zf-CCCH	136..161	CDD:279036	22/24 (92%)
		zf-CCCH	174..198	CDD:279036	20/23 (87%)
Zfp36l2	XP_008763271.1	Tis11B_N	3..141	CDD:282420	2/10 (20%)
		zf-CCCH	164..189	CDD:279036	22/24 (92%)
		zf-CCCH	202..226	CDD:279036	20/23 (87%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	61	1.000	Domainoid score	I10179
eggNOG	1	0.900	-	-		E1_COG5063
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000616
OrthoInspector	1	1.000	-	-		otm45321
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12547
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.870