DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tis11 and F38C2.7

DIOPT Version :9

Sequence 1:	NP_001259490.1	Gene:	Tis11 / 32222	FlyBaseID:	FBgn0011837	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_502930.1	Gene:	F38C2.7 / 185463	WormBaseID:	WBGene00009539	Length:	203	Species:	Caenorhabditis elegans

Alignment Length:	168	Identity:	46/168 - (27%)
Similarity:	69/168 - (41%)	Gaps:	32/168 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 SQPAQLIQQQQQQHQQQQQQQPAVASLVTITENLGNMNLHRKLERTQSEPLPPQQPMNTSRYKTE 139
            :|.:..:.|.:.:.:....|..|.....||.:     .||::::..:.:         ...:||.
Worm    42 AQFSLFVNQNETEQKLFSNQSLANRDPCTIPD-----ELHQEMKSLKKK---------EEAFKTS 92

  Fly   140 LCRPFEEAGECKYGEKCQFAHGSHELR---NVHRHPKYKTEYCRTFHSVGFCPYGPRCHFVHNAD 201
            ||.......:|.|||||:|||..||||   ....|..|||..|..|.:.|.|.||.||.|:|.
Worm    93 LCGFHRRGQKCAYGEKCKFAHSVHELRFPQTKRNHRNYKTVLCNNFSTTGHCKYGIRCQFIHR-- 155

  Fly   202 EARAQQAAQAAKSSTQSQSQSQQSSSQNFSPKSNQSSN 239
                         |..|.|.:|.:..:|.:...|..|:
Worm   156 -------------SMNSTSSNQSNKMENITIDLNVQSD 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_001259490.1	zf-CCCH	136..161	CDD:279036	12/24 (50%)
Tis11	NP_001259490.1	zf-CCCH	174..198	CDD:279036	12/23 (52%)
F38C2.7	NP_502930.1	zf-CCCH	89..115	CDD:279036	13/25 (52%)
F38C2.7	NP_502930.1	zf-CCCH	130..154	CDD:279036	12/23 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165267
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5063
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12547
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.800