Protein Alignment Tis11 and oma-2

DIOPT Version :9

• Sequence 1: NP_001259490.1
• Gene: Tis11 / 32222
• FlyBaseID: FBgn0011837
• Length: 436
• Species: Drosophila melanogaster
• Sequence 2: NP_505069.1
• Gene: oma-2 / 179183
• WormBaseID: WBGene00003865
• Length: 393
• Species: Caenorhabditis elegans
• Alignment Length: 444
• Identity: 101/444 - (22%)
• Similarity: 165/444 - (37%)
• Gaps: 126/444 - (28%)

  Fly    39 NEVRKEIRMLLAHGANLD--QQHQQQPHRHHGGLTRTISQPAQLIQQQQQQHQQQQQQQPAVASL 101
            ||.|.|..:..:|...::  .:.||:|..|...|   :|:.|.|:..::|..::
 Worm    12 NEARTESSVEPSHPDMMETVPEEQQKPISHIDDL---LSETANLMAVKEQLLKE----------- 62

  Fly   102 VTITENLGNMNLHRKLERTQSEPLPPQQ----PMNTSR------YKTELCRPFEEAGECKYGEKC 156
            :...|::.:|.: |.|:....|.:.|.|    |....|      |||.:|:.:.|:..|.:.|.|
 Worm    63 IAENEHIHSMQM-RALQNLPQEAILPLQYHADPRRRHRMQKPESYKTVICQAWLESKTCAFAENC 126

  Fly   157 QFAHGSHELR----NVHRHPKYKTEYCRTFHSVGFCPYGPRCHFVH--NADEA--RAQQAAQAAK 213
            :||||..|||    ...::.||:|:.|..:.:.|.||||.||.|:|  |...|  ||.:..:.::
 Worm   127 RFAHGEEELRPSLIEARQNNKYRTKLCDKYTTTGLCPYGKRCLFIHPDNGPNAYIRADKLFEVSQ 191

  Fly   214 SSTQSQSQSQQ-----------SSSQNF----------SPKSNQSSNQSSNSSSSSSSSGGGGGG 257
            ....:..:.|.           :..|.|          .|.:|.....:..|.
 Worm   192 RHALADLRDQMEHHIMNGGRSTAGPQQFDMFARPCTPDEPAANMPLGPTPVSI------------ 244

  Fly   258 GNSINNNNGSQFYLPLSPPLSMSTGSDRESPTGSLSLSPTN--SLTSF--------PFHDALQHG 312
                   .|.::.||...||......:|  |..|..|.|:.  :|.|.        ||...|
 Worm   245 -------RGPRYELPSKKPLETEEAGNR--PPSSWPLDPSTFFALDSLNMATRPISPFESML--- 297

  Fly   313 YLASNGAKSNSSASSTSSASGMGLGMSMGIGQGMIIGQGLGMGHHGPATPPESPNVPISPVHTPP 377
                .||..|...|.....|..| |:|             |....|.....:|.:.|::
 Worm   298 ----IGAAGNMQYSMLGKQSTPG-GVS-------------GYSSSGSTPSQDSDSSPLT------ 338

  Fly   378 PYDVVVSGSGAGN-----NSVGSKQLLQKSVSTPM-QQEDTPRLPVFNRLSSGV 425
                  :.|.|.:     ||..::.:|.||::.|| ..|.|..:|..::|:..:
 Worm   339 ------AASAAADAACQANSESAQSILLKSINNPMIGNETTLPIPGLDQLAMDI 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_001259490.1	zf-CCCH	136..161	CDD:279036	10/24 (42%)
		zf-CCCH	174..198	CDD:279036	11/23 (48%)
oma-2	NP_505069.1	zf-CCCH	10..>172	CDD:325094	50/174 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165259
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5063
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	76	1.000	Inparanoid score	I3841
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12547
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.890