DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tis11 and Y116A8C.19

DIOPT Version :9

Sequence 1:	NP_001259490.1	Gene:	Tis11 / 32222	FlyBaseID:	FBgn0011837	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_503019.1	Gene:	Y116A8C.19 / 178477	WormBaseID:	WBGene00013796	Length:	196	Species:	Caenorhabditis elegans

Alignment Length:	153	Identity:	44/153 - (28%)
Similarity:	75/153 - (49%)	Gaps:	30/153 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 QQHQQQQQQQPAVASLVTITENLGNMNLHRKLERTQSEPLPPQQPMNTSRYKTELCRPFEEAGE- 149
            :||:.::...      .||::     :||.:::|.:.:         ...:||.|| .|:..|:
Worm    54 KQHKSRKYDS------CTISD-----DLHDEMKRLKKK---------EEAFKTALC-GFQRRGQK 97

  Fly   150 CKYGEKCQFAHGSHELR-----NVHRHPKYKTEYCRTFHSVGFCPYGPRCHFVHNA-DEARAQQA 208
            |.|||:|:|||..||||     ..||:  |||..|..|.:.|:|.||.||.|:|.| ......::
Worm    98 CIYGEQCKFAHSVHELRFTQAKKTHRN--YKTVLCDKFSTTGYCKYGARCQFIHRALGSTSTTES 160

  Fly   209 AQAAKSSTQSQSQSQQSSSQNFS 231
            |:.|......:|...::.:.:::
Worm   161 AEMADFKLNVESDLSRAFALDYT 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_001259490.1	zf-CCCH	136..161	CDD:279036	13/25 (52%)
Tis11	NP_001259490.1	zf-CCCH	174..198	CDD:279036	12/23 (52%)
Y116A8C.19	NP_503019.1	zf-CCCH	84..110	CDD:279036	14/26 (54%)
Y116A8C.19	NP_503019.1	zf-CCCH	125..149	CDD:279036	12/23 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165268
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5063
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12547
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.800