DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tis11 and dct-13

DIOPT Version :9

Sequence 1:	NP_001259490.1	Gene:	Tis11 / 32222	FlyBaseID:	FBgn0011837	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_503017.1	Gene:	dct-13 / 178476	WormBaseID:	WBGene00013794	Length:	205	Species:	Caenorhabditis elegans

Alignment Length:	194	Identity:	58/194 - (29%)
Similarity:	83/194 - (42%)	Gaps:	37/194 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 AHGANLDQQHQQQPHRHHGGLTRTISQPAQLIQQQQQQHQQQQQQQPAVASL--VTITENLGN-- 110
            |..||..|....|      ..|.:..|.:.::|:.:..|:...    |:|:.  .||::.|..
Worm    29 AFPANSTQSLSSQ------SSTGSSDQHSVILQENESAHKLSS----AIANCDPCTISDELREEM 83

  Fly   111 MNLHRKLERTQSEPLPPQQPMNTSRYKTELCRPFEEAGECKYGEKCQFAHGSHELR---NVHRHP 172
            |.|.:|                ...:||.||...:....|.|||.|:||||.||||   ....|.
Worm    84 MRLKKK----------------EKAFKTSLCLSHKRGKTCIYGEACKFAHGVHELRCQQTTRNHR 132

  Fly   173 KYKTEYCRTFHSVGFCPYGPRCHFVHNA-DEARAQQAAQAA--KSSTQSQ-SQSQQSSSQNFSP 232
            .|||..|..|.:.|:|.||.||.|:|.: |...|.:..:.|  |.:.||. |::....|.:|.|
Worm   133 NYKTVLCDKFTTTGYCKYGARCQFIHRSMDTTPAAKPMETADFKPNVQSDLSRAFALDSSSFLP 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_001259490.1	zf-CCCH	136..161	CDD:279036	11/24 (46%)
Tis11	NP_001259490.1	zf-CCCH	174..198	CDD:279036	12/23 (52%)
dct-13	NP_503017.1	zf-CCCH	93..119	CDD:279036	12/25 (48%)
dct-13	NP_503017.1	zf-CCCH	134..158	CDD:279036	12/23 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165270
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5063
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12547
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.800