Protein Alignment Tis11 and mex-5

DIOPT Version :9

• Sequence 1: NP_001259490.1
• Gene: Tis11 / 32222
• FlyBaseID: FBgn0011837
• Length: 436
• Species: Drosophila melanogaster
• Sequence 2: NP_502566.1
• Gene: mex-5 / 178296
• WormBaseID: WBGene00003230
• Length: 468
• Species: Caenorhabditis elegans
• Alignment Length: 445
• Identity: 97/445 - (21%)
• Similarity: 140/445 - (31%)
• Gaps: 182/445 - (40%)

  Fly    11 EQDDSHYF--------------ERGDISKYVTMNDHLGDFDCNEVRKEIRMLLAHGANLDQQHQQ 61
            :|...:||              :.|...:|.....:..|.:...|:     :.|:|:...|||..
 Worm    36 DQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQ-----VPANGSMAPQQHMM 95

  Fly    62 ---QPHRHHGGLTRTISQPAQLIQQQQQQHQQQ-------------------------------- 91
               ||:.:       ::||.|..||..|..|.|
 Worm    96 VSGQPYLY-------MAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGV 153

  Fly    92 ---------QQQQP----------AVASLV------------TITENLGNMNL----HRKLER-- 119
                     .||||          ..|.|.            |:..:..|.|:    ||.:|.
 Worm   154 MPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDE 218

  Fly   120 -----------------TQSE-------------------PLP---PQQPMNTSRYKTELCRPFE 145
                             |.|.                   |:|   .|||.|   |||.||. ..
 Worm   219 LPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPN---YKTRLCM-MH 279

  Fly   146 EAG--ECKYGEKCQFAHGSHELRNVH---RHP--KYKTEYCRTF--HSVGFCPYGPRCHFVHNAD 201
            .:|  .|..|.:|:||||..|||...   |:|  ||||:.|:.|  ...||||||.||.|||..|
 Worm   280 ASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTD 344

  Fly   202 EARAQQAAQAAKSSTQSQSQSQQSSSQNF-----SPKSNQSSNQS-------------SNSSSSS 248
            : ..|......:.|...|...|....:::     .|:..::..::             :.|....
 Worm   345 K-EFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCL 408

  Fly   249 SSSGGGGGGGNSINNNNGSQFYLP--------LSPPL-----SMSTGSDRESPTG 290
            |::|.....|...|....::..||        .:||:     |:||....|...|
 Worm   409 SNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLG 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_001259490.1	zf-CCCH	136..161	CDD:279036	11/26 (42%)
		zf-CCCH	174..198	CDD:279036	14/25 (56%)
mex-5	NP_502566.1	ZnF_C3H1	270..298	CDD:214632	13/31 (42%)
		zf-CCCH	315..342	CDD:279036	15/26 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165258
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5063
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12547
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840