Protein Alignment Tis11 and oma-1

DIOPT Version :10

• Sequence 1: NP_511141.2
• Gene: Tis11 / 32222
• FlyBaseID: FBgn0011837
• Length: 436
• Species: Drosophila melanogaster
• Sequence 2: NP_501542.1
• Gene: oma-1 / 177703
• WormBaseID: WBGene00003864
• Length: 407
• Species: Caenorhabditis elegans
• Alignment Length: 492
• Identity: 114/492 - (23%)
• Similarity: 168/492 - (34%)
• Gaps: 171/492 - (34%)

  Fly     8 KSREQDDSHYFE---RGDISKYVTMNDHLGDFDCNEVRKEIRMLLAHGANLDQQHQQQPHRHHGG 69
            ::.|:.|.|:.|   .|..:..|:..||..|..                      |..|:...|.
 Worm     6 ENNEKIDEHHLESSLAGVPTLPVSPLDHAKDLS----------------------QTNPNAQIGD 48

  Fly    70 LTRTISQPAQLIQQQQQ--------QHQQQQQQQPAVASLVTITENLGNMNLHRKLERTQSEPLP 126
            |   ::|.|.||..::|        ||.|..|    |.::.:..:|              ::..|
 Worm    49 L---VTQTANLIAIKKQLLEDIAFNQHIQSMQ----VRAIQSFPQN--------------NQVAP 92

  Fly   127 PQQPMNTSR-----------YKTELCRPFEEAGECKYGEKCQFAHGSHELRNVHRHP----KYKT 176
            |.|..:..|           |||.:|:.:.|:..|.:.:.|:||||..|||.....|    ||||
 Worm    93 PFQQFDPRRRGLARMQKPESYKTVICQAWLESKTCSFADNCRFAHGEEELRPTFVEPLQNNKYKT 157

  Fly   177 EYCRTFHSVGFCPYGPRCHFVH-----NADEARAQQAAQAAKSSTQSQSQSQQSSSQNFSPKSNQ 236
            :.|..:.:.|.||||.||.|:|     || ..||.:..:.::....:..:.|.  .|:..
 Worm   158 KLCDKYTTTGLCPYGKRCLFIHPDHGPNA-YIRADKLLEVSQRHALADIRDQM--EQHIM----- 214

  Fly   237 SSNQSSNSSSSSSSSGGGGGGGNSINNNNGSQFYLPLSP---PLSM-STGSDRESPTGSLSLSPT 297
                                       .||.....|||.   ||.| :..|..:.|...|.|.||
 Worm   215 ---------------------------TNGRIAAPPLSAIQHPLEMFARPSTPDEPAAKLPLGPT 252

  Fly   298 NSLTSFP--------FHDALQHGYLASNGAKS------------------NSSASSTSSASGMGL 336
            ...|..|        .|||        .||.:                  |.:....|....|.|
 Worm   253 PVSTRGPRYELPTKELHDA--------EGAMTYPPSRWPLDPSMFALDAWNMAHRPASPLDSMVL 309

  Fly   337 GMSMGIGQ-GMIIGQGLGMGHHGPATPPESPNVPISPVHTPPPYDVVVSGSGAGN---------N 391
            |.:...|. ||:..|....|..|           .|...:.|..|:..|...|.:         |
 Worm   310 GSAPNAGSFGMLGKQNTPGGVSG-----------YSSAGSTPSQDLSSSSLNAASAAAAAAYFAN 363

  Fly   392 SVGSKQLLQKSVST-PMQQEDTP--RLPVFNRLSSGV 425
            |..::.||.|||:| ||...:.|  .:|.|::|:..:
 Worm   364 SAVAQSLLMKSVATDPMMSCNGPFSPMPGFDQLAENM 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_511141.2	CTH1	<121..>198	CDD:227395	32/91 (35%)
oma-1	NP_501542.1	CTH1	<94..179	CDD:227395	30/84 (36%)