Protein Alignment Tis11 and mex-6

DIOPT Version :10

• Sequence 1: NP_511141.2
• Gene: Tis11 / 32222
• FlyBaseID: FBgn0011837
• Length: 436
• Species: Drosophila melanogaster
• Sequence 2: NP_496043.1
• Gene: mex-6 / 174504
• WormBaseID: WBGene00003231
• Length: 467
• Species: Caenorhabditis elegans
• Alignment Length: 296
• Identity: 76/296 - (25%)
• Similarity: 111/296 - (37%)
• Gaps: 75/296 - (25%)

  Fly    54 NLDQQHQQQPHRHHGGLTRTI----------SQPAQLIQQQQQQHQQQQQQQPA--------VAS 100
            |..|..|.:........|||:          |:..:.:|:.:.::.|.:.|.|.        ..|
 Worm   164 NPQQSEQLRKSGAQISTTRTVPLTSSTPLPTSREYETVQRDRNRNSQSRYQCPIEHDDLPIDEIS 228

  Fly   101 LVTI-----------TENLGNMNLHRKL-ERTQSEP-LPPQQPMNTSRYKTELCRPFEEAG--EC 150
            .:||           .||..|.|...|| .|..::| :..|.|.|   :||.||.. ..||  .|
 Worm   229 KITIDNHNDDTMSAEKENRFNKNRVEKLGRRGFAKPEVDSQLPHN---FKTRLCMT-HAAGINPC 289

  Fly   151 KYGEKCQFAHGSHELRNVH---RHP--KYKTEYCRTF--HSVGFCPYGPRCHFVHNADEARAQQA 208
            ..|.:|:||||..|||...   |:|  ||||:.|:.|  ...|.||||.||.|||.:|.......
 Worm   290 ALGARCKFAHGLKELRASDIPTRYPNNKYKTKLCKNFARGGSGVCPYGLRCEFVHPSDTEFQNIP 354

  Fly   209 AQAAKSSTQSQSQSQQSSSQNFSPKSNQSSNQSSN------------------SSSSSSSSGGGG 255
            ....|...:..|..:......:.|:...:|.:::.                  |::......||.
 Worm   355 PYQRKMVEEHDSIPEDYVVARYQPRFMHTSGKATTPTKVTLKQRNVAGSMMCLSNTGRDLEAGGD 419

  Fly   256 GGGNSINNNNGSQFYLPL--------SPPLSMSTGS 283
            .....||.|:     ||.        :||::.|..|
 Worm   420 FNHPEINEND-----LPPHLRRIRRGNPPVTRSRPS 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_511141.2	CTH1	<121..>198	CDD:227395	36/86 (42%)
mex-6	NP_496043.1	PAT1	<50..>186	CDD:401645	6/21 (29%)
		CTH1	157..>359	CDD:227395	60/198 (30%)
		zf-CCCH	318..345	CDD:459885	14/26 (54%)