Protein Alignment Tis11 and Tis11

DIOPT Version :10

• Sequence 1: NP_511141.2
• Gene: Tis11 / 32222
• FlyBaseID: FBgn0011837
• Length: 436
• Species: Drosophila melanogaster
• Sequence 2: XP_061511893.1
• Gene: Tis11 / 1271010
• VectorBaseID: AGAMI1_006953
• Length: 539
• Species: Anopheles gambiae
• Alignment Length: 497
• Identity: 187/497 - (37%)
• Similarity: 233/497 - (46%)
• Gaps: 170/497 - (34%)

  Fly    52 GANLDQQHQQQ--------------------PHRHHGG----LTRTISQPA--QLIQQQQQQHQQ 90
            |:|...|||||                    .|:||||    |.||.||||  .:::...:....
Mosquito    99 GSNHHIQHQQQQLQYQQQQYSYNLQKTGGASQHKHHGGHHAALHRTASQPAARHMVENILEMFTL 163

  Fly    91 QQQQQPA------------VASLVT-----------------------ITENLGNMNLHRKLERT 120
            .:..:.|            ||:.::                       .|.|..:.:.|||||||
Mosquito   164 NKAMEDAALAGLTGTTAATVAATISSSSSSASSINSNHGNNGSHNQQHATSNTSSSSGHRKLERT 228

  Fly   121 QSEPLPPQQPMNTSRYKTELCRPFEEAGECKYGEKCQFAHGSHELRNVHRHPKYKTEYCRTFHSV 185
            ||||||  |.:||||||||||||:|||||||||:|||||||..||||:.||||||||.|||||||
Mosquito   229 QSEPLP--QQVNTSRYKTELCRPYEEAGECKYGDKCQFAHGMQELRNLQRHPKYKTELCRTFHSV 291

  Fly   186 GFCPYGPRCHFVHNADEAR--------------AQQAAQAAKSSTQSQSQSQQSSSQNFSPKSNQ 236
            |||||||||||||||:|||              |..||.||.::..:.|||.|.::     ||||
Mosquito   292 GFCPYGPRCHFVHNAEEARNHNRNVAAYHARLAAANAAAAAAAANGNSSQSAQGAA-----KSNQ 351

  Fly   237 S--SNQSSNSSSSSSSSGGGGGGGNS--------------------------INNNNGSQ----- 268
            :  |..:||::||....|......:|                          :.:::..|
Mosquito   352 NGPSMIASNNNSSQQQHGHHQQQQHSALKSLSVAQQLQTAAAAAAILQQQQQLQHHHHQQQQHQH 416

  Fly   269 -FYLPLSPPLSMSTGSDRESPTGSLSLSPTNSLTSFPFHDALQHGYLASNGAKSNSSASSTSSAS 332
             ..|||||.|||||||||.||.||||||||.|:.:| |.:|:                |.|....
Mosquito   417 LHQLPLSPALSMSTGSDRASPIGSLSLSPTTSMANF-FPEAI----------------SPTLQQG 464

  Fly   333 GMGLGMSMGIGQGMIIGQGLGMGHHGPATPPESPNVPISPVHTPPPYD-----VVVSGSGAGNNS 392
            |       .|.|..:.          |.:||.||...:||:.:|||..     :.:.|..||..:
Mosquito   465 G-------AIPQPFLF----------PNSPPASPIEGLSPMASPPPSSPSLTTMKLGGGAAGGCN 512

  Fly   393 VGSKQLLQKSVSTPMQQEDTPRLPVFNRLSSGVEAYQQQSNL 434
            .||             .||  ||||||||||.:|.:....||
Mosquito   513 GGS-------------VED--RLPVFNRLSSALEPFVVNLNL 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tis11	NP_511141.2	CTH1	<121..>198	CDD:227395	65/76 (86%)
Tis11	XP_061511893.1	None