Protein Alignment CkIalpha and Csnk1a1

DIOPT Version :10

• Sequence 1: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: XP_006526446.1
• Gene: Csnk1a1 / 93687
• MGIID: 1934950
• Length: 374
• Species: Mus musculus
• Alignment Length: 358
• Identity: 253/358 - (70%)
• Similarity: 281/358 - (78%)
• Gaps: 36/358 - (10%)

  Fly    10 SRPEIIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGV 74
            |:.|.||||||:::|||||||||||||.::|.:|||||:|:||..|||||||||:|||:||.|||
Mouse     7 SKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGV 71

  Fly    75 GFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRD 139
            |.|.||.:|:||::|.|||||||||||||||||:|.||:||||||.||||.|:||:|.|.|||||
Mouse    72 GIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRD 136

  Fly   140 IKPDNFLMGIGRHCNK----------------------------LFLIDFGLAKKFRDPHTRHHI 176
            ||||||||||||||||                            |||||||||||:||..||.||
Mouse   137 IKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSPSQDPSFSGLNQLFLIDFGLAKKYRDNRTRQHI 201

  Fly   177 VYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISE 241
            .||||||||||||||||||||||||||||||||||||:|||||..|||||:||.||:||||||||
Mouse   202 PYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISE 266

  Fly   242 KKMSTPIEVLCKGSPAEFSMYLNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQ 306
            ||||||:||||||.||||:|||||||.|||||.|||||||||||||||||||||||.:|||||||
Mouse   267 KKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQ 331

  Fly   307 K--------THQGQPNPAILLEQLDKDKEKQNG 331
            |        :.|||.......:|.||.|....|
Mouse   332 KAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKG 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	216/292 (74%)
Csnk1a1	XP_006526446.1	STKc_CK1_alpha	16..309	CDD:271030	216/292 (74%)