Protein Alignment CkIalpha and HRR25

DIOPT Version :10

• Sequence 1: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_015120.1
• Gene: HRR25 / 855897
• SGDID: S000006125
• Length: 494
• Species: Saccharomyces cerevisiae
• Alignment Length: 311
• Identity: 183/311 - (58%)
• Similarity: 244/311 - (78%)
• Gaps: 0/311 - (0%)

  Fly    13 EIIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGVGFP 77
            ::.||.|:|:.||||||||||||.|.::.||||||||:||..:|||||.||:::||.||||||.|
Yeast     2 DLRVGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIP 66

  Fly    78 RIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKP 142
            .||..|:|..:|.:|:||||||||||||:|.|.|:.|||:||..||..|::|||.:.||||||||
Yeast    67 FIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRRFSFKTVIMLALQMFCRIQYIHGRSFIHRDIKP 131

  Fly   143 DNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSRRDDM 207
            ||||||:||..:.:.:|||||:||:||.:|..||.|||:|:|||||||||:|.|||||||||||:
Yeast   132 DNFLMGVGRRGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQSRRDDL 196

  Fly   208 ESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYLNYCRSLRFE 272
            ||||||::||.:|.|||||:||.||:|||::|.|||::..:|.||.|.|.||..|:.||::|:|:
Yeast   197 ESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFD 261

  Fly   273 EQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQKTHQGQPNPAILLEQLD 323
            |:|||::|.:||:.|...|.:..|:::|||||:......:....:|:|:.|
Yeast   262 EKPDYLFLARLFKDLSIKLEYHNDHLFDWTMLRYTKAMVEKQRDLLIEKGD 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	168/264 (64%)
HRR25	NP_015120.1	Protein Kinases, catalytic domain	8..282	CDD:473864	172/273 (63%)