Protein Alignment CkIalpha and YCK2

DIOPT Version :10

• Sequence 1: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_014245.1
• Gene: YCK2 / 855568
• SGDID: S000005098
• Length: 546
• Species: Saccharomyces cerevisiae
• Alignment Length: 343
• Identity: 164/343 - (47%)
• Similarity: 209/343 - (60%)
• Gaps: 20/343 - (5%)

  Fly     9 ESRPE-IIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSG 72
            :||.: .|||..|::.:|||.||||.::.|.::.:|..||||.|......|||..|.:.|:||:|
Yeast    64 QSRDDSTIVGLHYKIGKKIGEGSFGVLFEGTNMINGLPVAIKFEPRKTEAPQLKDEYRTYKILAG 128

  Fly    73 GVGFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIH 137
            ..|.|:..:.|:|...|.||:|||||||||||::|.|.|::|||:.:..|||..:|.:|....|:
Yeast   129 TPGIPQEYYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSVKTVVQVAVQMITLIEDLHAHDLIY 193

  Fly   138 RDIKPDNFLMGIGR----HCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLG 198
            |||||||||  |||    ..||:.|||||:||::|||.|:.||.|||.|:|:|||||.|||.|||
Yeast   194 RDIKPDNFL--IGRPGQPDANKVHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLG 256

  Fly   199 IEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYL 263
            .|||||||||::|:|..||.||.|||||:||...:||||||.|||..|.:..|.:|.|.:|..||
Yeast   257 REQSRRDDMEAMGHVFFYFLRGQLPWQGLKAPNNKQKYEKIGEKKRLTNVYDLAQGLPIQFGRYL 321

  Fly   264 NYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTML------------KQKTH-QGQPNP 315
            ...|:|.|||.|||...|.|...:...|....|..|||..|            |...| .|.|||
Yeast   322 EIVRNLSFEETPDYEGYRMLLLSVLDDLGETADGQYDWMKLNGGRGWDLSINKKPNLHGYGHPNP 386

  Fly   316 AILLEQLDKDKEKQNGKP 333
            .....:..:.|..|...|
Yeast   387 PNEKSKRHRSKNHQYSSP 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	143/268 (53%)
YCK2	NP_014245.1	STKc_CK1_fungal	75..351	CDD:271029	145/277 (52%)