Protein Alignment CkIalpha and TTBK1

DIOPT Version :9

• Sequence 1: NP_001162737.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: XP_016866853.1
• Gene: TTBK1 / 84630
• HGNCID: 19140
• Length: 1409
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 113/364 - (31%)
• Similarity: 173/364 - (47%)
• Gaps: 61/364 - (16%)

  Fly    15 IVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGVGFPRI 79
            :|..:::|::|||.|.||:||..|.:.:.|.||:|:|||......|..|..:.:.|.|.....|.
Human    29 VVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRF 93

  Fly    80 RHHGKEKNFNTLVMDLLGPSLEDLFNFCTR-HFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPD 143
            ...|:.:.||.:||.|.|.:|.||.....| .||:.|.|.|..|::..:|.||...|:||||||.
Human    94 IGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPS 158

  Fly   144 NFLMG-IGRHCNKLFLIDFGLAKKF-------RDPHTRHHIVYREDKNLTGTARYASINAHLGIE 200
            ||.|| :.....|.:::|||||:::       |.|        |......||.||||:|||...|
Human   159 NFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPP--------RNVAGFRGTVRYASVNAHKNRE 215

  Fly   201 QSRRDDMESLGYVMMYFNRGVLPWQGMKANTK----QQKYEKISEKKMSTPIEVLCKGSPAEFSM 261
            ..|.||:.||.|:::.|..|.|||:.:|...:    ::|||.          .:|.|..|:||.:
Human   216 MGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEH----------RMLLKHMPSEFHL 270

  Fly   262 YLNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDW--------------TMLKQKTHQG- 311
            :|::..||.:..:|||..:..:|....:......:..:||              |..:|.|.|.
Human   271 FLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTA 335

  Fly   312 --------QPNPAILLEQLDKD-------KEKQNGKPLI 335
                    .|.|..||.:..:|       .:::|..|::
Human   336 AMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPIL 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_001162737.1	PKc_like	19..284	CDD:304357	98/277 (35%)
		Pkinase_Tyr	23..284	CDD:285015	97/273 (36%)
TTBK1	XP_016866853.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810