Protein Alignment CkIalpha and csnk1g2a

DIOPT Version :10

• Sequence 1: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: XP_005171263.1
• Gene: csnk1g2a / 554152
• ZFINID: ZDB-GENE-030131-6445
• Length: 452
• Species: Danio rerio
• Alignment Length: 331
• Identity: 158/331 - (47%)
• Similarity: 222/331 - (67%)
• Gaps: 23/331 - (6%)

  Fly    14 IIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGVGFPR 78
            ::||..:||.:|||.|:||::.||.::.:.|.||||:|...:|.|||..|.:.|:.|....|.|:
Zfish    44 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGNAEGVPQ 108

  Fly    79 IRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPD 143
            :.:.|....:|.:|::||||||||||:.|.|.|::|||||:..|:|.|:|::|.:..|:||:||:
Zfish   109 VYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLITRMEFVHTRSLIYRDVKPE 173

  Fly   144 NFLMGIGRHCNK----LFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSRR 204
            |||  :||...|    :.:|||||||::.||.|:.||.|||.|:|||||||.|||.|||.|||||
Zfish   174 NFL--VGRPGTKRQHTIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRR 236

  Fly   205 DDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYLNYCRSL 269
            ||:|:||::.|||.||.|||||:||:|.:::|:||.:.|.:|||||||:..| |.:.||.|.|.|
Zfish   237 DDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCESFP-EMATYLRYVRRL 300

  Fly   270 RFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQKTHQGQPNPAIL--------LEQLDKDK 326
            .|.|:|||.|||:||..||....:.:||.|||.        |:|.|..:        |:..::||
Zfish   301 DFFERPDYEYLRKLFTDLFDRNGYVFDYEYDWV--------GKPLPTPIGPMPSDTPLQPSNRDK 357

  Fly   327 EKQNGK 332
            .:...|
Zfish   358 AQPQTK 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	140/268 (52%)
csnk1g2a	XP_005171263.1	STKc_CK1_gamma	49..335	CDD:271028	149/296 (50%)
		CK1gamma_C	335..422	CDD:463640	6/29 (21%)