Protein Alignment CkIalpha and gish

DIOPT Version :10

• Sequence 1: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_001262624.1
• Gene: gish / 49701
• FlyBaseID: FBgn0250823
• Length: 537
• Species: Drosophila melanogaster
• Alignment Length: 339
• Identity: 161/339 - (47%)
• Similarity: 222/339 - (65%)
• Gaps: 19/339 - (5%)

  Fly    14 IIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGV---- 74
            ::||..:||.:|||.|:||::.||.::.:.|.||||||...::.|||..|.:.|::|....
  Fly    56 LMVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKMEPMKSKAPQLHLEYRFYKLLGSHADNAP 120

  Fly    75 -GFPRIRHHGK-EKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIH 137
             |.|||.|.|. ...:|.:|::|||.|||||||.|.|.|::|||||:..|::.|:||:|.:..|:
  Fly   121 DGIPRIYHLGTCGGRYNAMVLELLGLSLEDLFNICARKFSLKTVLMIAKQLLHRIEYVHSRHLIY 185

  Fly   138 RDIKPDNFLMGIGRHCNK----LFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLG 198
            ||:||:|||  |||...|    :.:|||||||::.|..|..||.|||.|:|||||||.|||.|:|
  Fly   186 RDVKPENFL--IGRTSTKREKIIHIIDFGLAKEYIDLDTNRHIPYREHKSLTGTARYMSINTHMG 248

  Fly   199 IEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYL 263
            .|||||||:|:||::.|||.||.|||||:||:|.:::|:||.:.|.:|||||||.|.|.||:.||
  Fly   249 REQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCDGHPEEFATYL 313

  Fly   264 NYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQKTHQG--QPNPAILLEQLDKDK 326
            .|.|.|.|.|.|||.:||:||:.||....:..:..:|||.....|..|  |....:::.. :||:
  Fly   314 RYVRRLDFFETPDYDFLRRLFQDLFDRKGYTDEGEFDWTGKTMSTPVGSLQTGHEVIISP-NKDR 377

  Fly   327 E----KQNGKPLIA 336
            .    |.|.|..:|
  Fly   378 HNVTAKTNAKGGVA 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	143/274 (52%)
gish	NP_001262624.1	STKc_CK1_gamma	61..354	CDD:271028	150/294 (51%)
		CK1gamma_C	354..439	CDD:463640	9/39 (23%)