DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CkIalpha and csnk1g1

DIOPT Version :9

Sequence 1:	NP_001162737.1	Gene:	CkIalpha / 32221	FlyBaseID:	FBgn0015024	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	XP_009301749.1	Gene:	csnk1g1 / 494092	ZFINID:	ZDB-GENE-041212-63	Length:	466	Species:	Danio rerio

Alignment Length:	304	Identity:	158/304 - (51%)
Similarity:	212/304 - (69%)	Gaps:	14/304 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SRPE--------IIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKL 66
            |||.        ::||..:||.:|||.|:||::.||.::.:.|.||||:|...:|.|||..|.:.
Zfish    26 SRPSSSSASSGVLMVGPNFRVGKKIGCGNFGELKLGKNLYTNEYVAIKLEPVKSRAPQLHLEYRF 90

  Fly    67 YRILSGGVGFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIH 131
            |:.|....|.|::.:.|....:|.:|::||||||||||:.|.|.|::|||||:..|:|.|:||:|
Zfish    91 YKTLGSADGLPQVFYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVH 155

  Fly   132 LKCFIHRDIKPDNFLMGIGRHCNK----LFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYAS 192
            .|..|:||:||:|||  |||..||    :.:|||||||::.||.|:.||.|||.|:|||||||.|
Zfish   156 SKNLIYRDVKPENFL--IGRQGNKKEHIIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMS 218

  Fly   193 INAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPA 257
            ||.|||.|||||||:|:||::.|||.||.|||||:||:|.:::|:||.:.|.:|||||||:..|.
Zfish   219 INTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEVLCENFPE 283

  Fly   258 EFSMYLNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDW 301
            |.:.||.|.|.|.|.|:|||.|||.||..||....:.:||.|||
Zfish   284 EMATYLRYVRRLDFFEKPDYDYLRNLFTELFDRKGYAFDYSYDW 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_001162737.1	PKc_like	19..284	CDD:304357	144/268 (54%)
CkIalpha	NP_001162737.1	Pkinase_Tyr	23..284	CDD:285015	142/264 (54%)
csnk1g1	XP_009301749.1	STKc_CK1_gamma	43..330	CDD:271028	153/287 (53%)
		SPS1	43..>265	CDD:223589	119/223 (53%)
		CK1gamma_C	330..417	CDD:289378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910