Protein Alignment CkIalpha and csnk1db

DIOPT Version :10

• Sequence 1: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_998415.1
• Gene: csnk1db / 406533
• ZFINID: ZDB-GENE-040426-2385
• Length: 409
• Species: Danio rerio
• Alignment Length: 318
• Identity: 205/318 - (64%)
• Similarity: 255/318 - (80%)
• Gaps: 7/318 - (2%)

  Fly    13 EIIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGVGFP 77
            |:.||.:||:.||||||||||||||..|..|||||||:|....:||||..|:|:|:::.||||.|
Zfish     2 ELRVGNRYRLGRKIGSGSFGDIYLGTDISVGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIP 66

  Fly    78 RIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKP 142
            .|:..|.|.::|.:||:|||||||||||||:|.|::||||:|.||||.|:||||.|.|||||:||
Zfish    67 TIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKP 131

  Fly   143 DNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSRRDDM 207
            ||||||:|:..|.:::||||||||:||..|..||.|||:|||||||||||||.|||||||||||:
Zfish   132 DNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDL 196

  Fly   208 ESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYLNYCRSLRFE 272
            ||||||:||||.|.|||||:||.||:||||:||||||||||||||||.|:||:.|||:||||||:
Zfish   197 ESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFD 261

  Fly   273 EQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQKTHQGQPNPAILLEQLDKDKEKQN 330
            ::|||.|||||||.||......|||::||.|||...::       ..|:.|:::.:::
Zfish   262 DKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGANR-------TAEEADRERRERD 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	187/264 (71%)
csnk1db	NP_998415.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	192/273 (70%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..409		2/13 (15%)
		Autoinhibitory. /evidence=ECO:0000250	317..341