Protein Alignment CkIalpha and Vrk2

DIOPT Version :9

• Sequence 1: NP_001162737.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: XP_008768654.1
• Gene: Vrk2 / 360991
• RGDID: 1311585
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 296
• Identity: 92/296 - (31%)
• Similarity: 146/296 - (49%)
• Gaps: 38/296 - (12%)

  Fly    17 GGKYRVIRKIGSGSFGDIYLGMSIQSGEEVA---IKMESAHARHPQLLYEAKLYRILS------- 71
            |.::.:.:.||||.||.|||.......|:.|   ||:|  :..:..|..|.|.|:..:
  Rat    26 GNQWALGKMIGSGGFGLIYLAFPTNKPEKDARHVIKVE--YQENGPLFSELKFYQRAAKRECIQK 88

  Fly    72 -------GGVGFPRIRHHG----KEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIG 125
                   ..:|.|.....|    |.:::..:||:.||..|:.|.| ....|...|||.|..:|:.
  Rat    89 WVKQRKLDYLGVPVFYGFGLTDFKGRSYRFMVMERLGIDLQKLLN-QNGAFKKLTVLQLGIRMLD 152

  Fly   126 RLEYIHLKCFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYRED--KNLTGTA 188
            .|||||...::|.|||..|.|:|.. :.::::|.|:||:  :|.....:|..|.||  |...||.
  Rat   153 VLEYIHENEYVHGDIKAANLLLGYA-NPDRVYLADYGLS--YRYCPNGNHKQYHEDPRKGHNGTL 214

  Fly   189 RYASINAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKAN--TKQQKYEKISEKKMSTPIEVL 251
            .:.|::||.|:..|||.|:|.|||.|:.:..|.|||:....|  ..|....|:.::...:.::..
  Rat   215 EFTSLDAHKGVAPSRRSDVEILGYCMLRWLCGKLPWETNLENPVAVQTAKTKLLDELPESVLKWT 279

  Fly   252 CKGSP----AEFSMYLNYCRSLRFEEQPDYMYLRQL 283
            ..||.    |||.||::   :|.::.:|||..|:::
  Rat   280 TSGSSCRELAEFFMYVH---NLAYDAKPDYQKLKKI 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_001162737.1	PKc_like	19..284	CDD:304357	91/294 (31%)
		Pkinase_Tyr	23..284	CDD:285015	91/290 (31%)
Vrk2	XP_008768654.1	PKc_like	16..314	CDD:304357	92/296 (31%)
		Pkinase	29..290	CDD:278497	81/266 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810